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Non-Infectious Uveitis: Optimising the Therapeutic Response
Drugs, 2015Non-infectious uveitis mainly affects the working-age population and can contribute to significant social and economic burden. It comprises a heterogeneous group of conditions with varied aetiology. Precise and early diagnosis, excluding masquerade syndromes, is the key to early therapeutic intervention.
Archana, Airody +3 more
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General Principles for the Treatment of Non-Infectious Uveitis
Inflammation & Allergy-Drug Targets, 2009Ocular inflammatory disorders constitute a sight-threatening group of diseases that might be managed according to their severity. Their treatment guidelines experience constant changes with new agents that improve the results obtained with former drugs.
Manuel, Díaz-Llopis +3 more
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Infectious and non infectious triggers in non‐infectious uveitis
Acta Ophthalmologica, 2010Abstract Purpose The induction of autoimmune uveitis is difficult to explain with respect to the immune privileged status of the eye. The intact BRB can only be passed by already activated leukocytes, which should normally be ignorant to the sequestered intraocular antigens.
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Intravitreal dexamethasone implants for non‐infectious uveitis
Clinical & Experimental Ophthalmology, 2019AbstractImportanceInflammatory‐mediated cystoid macular oedema (CMO) is the most common inflammatory‐mediated threat to vision in non‐infectious uveitis (NIU). Corticosteroid therapy is the cornerstone to the management of CMO in NIU. Sustained‐release dexamethasone (DEX) implant devices provide localized therapy.BackgroundThe authors present a series ...
Matthew McCartney +2 more
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Diagnosis and Management of Non-Infectious Uveitis in Pediatric Patients
Pediatric Drugs, 2023Uveitis in children accounts for 5-10% of all cases. The causes vary considerably. Classically, uveitis is distinguished according to its infectious or inflammatory origin and whether it is part of a systemic disease or represents an isolated ocular disease.
Ai Tien Nguyen +2 more
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Non‐infectious causes of uveitis in 70 Swiss children
Acta Paediatrica, 2000Many diseases are linked with uveitis, but few studies have specifically looked at the noninfectious triggers of childhood uveitis in Central Europe. The charts of 70 paediatric patients with non‐infectious uveitis admitted to the Department of Pediatrics, University of Bern, Switzerland, between 1983 and 1998 were therefore reviewed.
Stoffel PB +5 more
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Chronic Non-Infectious Uveitis in the Elderly
Drugs & Aging, 2006Intraocular inflammatory diseases are collectively known as uveitis. The aetiology of this condition can be diverse, as inflammation may result from direct involvement of the uveal tract or indirect inflammation of adjacent tissues. Uveitis can present challenges to diagnosis and treatment, and is potentially a severe sight-threatening disease.
Rajen, Gupta, Philip I, Murray
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Intravitreal immunotherapy in non-infectious uveitis
Expert Review of Clinical Pharmacology, 2023Introduction: In the past several years, there have been numerous advances in pharmacotherapeutics for the management of uveitis and other ocular inflammatory diseases, including newer therapeutic agents and ocular drug delivery systems. One of the most attractive modes of drug delivery is the intravitreal route since it has proven to be safe and ...
Menia, Nitin Kumar +2 more
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Adalimumab: A Review in Non-Infectious Non-Anterior Uveitis
BioDrugs, 2017Adalimumab (Humira®) is a tumour necrosis factor (TNF)-α inhibitor available in various countries worldwide, including the USA, Japan and those of the EU, for the treatment of non-infectious intermediate, posterior and panuveitis in adults. It is the first biological agent approved for this indication.
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