Results 71 to 80 of about 10,417,976 (225)

Exome Sequencing Uncovers Phenotypic and Genotypic Heterogeneity in 196 Indian Families Evaluated for Autoinflammatory Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger, Periyasamy Radhakrishnan, Suma Balan, Anand P. Rao, Prajna Udupa, Karthik Vijay Nair, Bhagesh Hunakunti, Adarsh Pooradan Prasannakumar, Sanket Limaye, Huzail Gani Shaikh, Rohit Naik, Mahesh Janarthanan, Sudharshan Sridharan, Vishal Sondhi, Sheela Nampoothiri, Hitesh Shah, Sabrinath Mahadevan, Mahabaleshwar Mamadapur, Devang Pandya, Katta Mohan Girisha, Abhay Shivpuri, Amita Moirangthem, Jyothi Raghuram, Gandham Sri Lakshmi Bhavani, Sachin Jeevanagi, Girish Subramaniam, Amita Aggarwal, Anju Shukla, Dhanya Lakshmi Narayanan   +28 more
wiley   +1 more source

Clinical Variations of Uveitis in Immuno-Inflammatory Diseases. Review of the Literature. Part 1

Oftalʹmologiâ, 2022
Non-infectious uveitis is one of the main and insufficiently studied causes of disability and blindness in patients with immuno-inflammatory diseases. Uveitis associated with spondyloarthritis, Behcet’s disease, juvenile idiopathic arthritis, systemic ...
G. A. Davydova, T. A. Lisitsyna, L. A. Kovaleva, E. S. Sorozhkina, A. A. Zaitseva, A. A. Baisangurova   +5 more
doaj   +1 more source

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

Animal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li, Qiang Luo, Xinglin Wu, Yuxiao Chen, Xuemei Tang   +4 more
wiley   +1 more source

Pediatric uveitis: a retrospective analysis at a tertiary eye care hospital in South India

Therapeutic Advances in Ophthalmology, 2021
Purpose: To analyze the demographics, etiology, complications, treatment modalities, and visual outcomes in pediatric uveitis patients at a tertiary eye care hospital.
Sowmya Raveendra Murthy, Sailatha Ganesh, Minija C.K., Nidhi Dubey   +3 more
doaj   +1 more source

Risk of Cancer According to Duration of Targeted Therapy Exposure in Spondyloarthritis: A Nationwide Cohort Study From the French Health Insurance Database

Arthritis &Rheumatology, EarlyView.
Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic, Pascal Claudepierre, Tat Thang Vo, Tran Trong Khoi Le, Siham Iggui, Laetitia Penso, Emilie Sbidian, Laura Pina Vegas   +7 more
wiley   +1 more source

Non-infectious causes of uveitis in 70 Swiss children

, 2000
Many diseases are linked with uveitis, but few studies have specifically looked at the noninfectious triggers of childhood uveitis in Central Europe.
von Vigier, R O, Sauvain, M J, Stoffel, P B, Beretta-Piccoli, B C, Ramelli, G P, Bianchetti, M G   +5 more
core   +1 more source

Pattern of uveitis in a referral ophthalmology center in Northeastern Thailand

Journal of Ophthalmic Inflammation and Infection
Purpose To report the characteristics and epidemiology of uveitis in a university-based referral center in northeastern Thailand and review the uveitis patterns present in various regions worldwide.
Trakanta Wannapanich, Waraporn Chuenchaem, Patanaree Luanratanakorn, Wipada Laovirojjanakul   +3 more
doaj   +1 more source

Rhegmatogenous retinal detachment in uveitis

Journal of Ophthalmic Inflammation and Infection, 2017
Background Retinal detachment is more common among uveitis patients than in the general population. Here, we aimed to assess the prevalence of rhegmatogenous retinal detachment (RRD) in a uveitis population. Methods We retrospectively studied 851 uveitis
Joeri De Hoog, Josianne C. Ten Berge, Fahriye Groen, Aniki Rothova   +3 more
doaj   +1 more source

Corticosteroid implants for chronic non-infectious uveitis. [PDF]

, 2016
BACKGROUND: Uveitis is a term used to describe a heterogeneous group of intraocular inflammatory diseases of the anterior, intermediate, and posterior uveal tract (iris, ciliary body, choroid).
Garg, Sunir J., Rahimy, Ehsan, Sieving, Pamela C., Tang, Johnny, Law, Hua Andrew, Brady, Christopher J, Villanti, Andrea C, Reddy, Rahul   +7 more
core   +1 more source

A systems approach to non-infectious uveitis [PDF]

, 2018
Non-infectious uveitis (NIU) refers to a group of intraocular inflammatory conditions with great variability in disease course, visual prognosis, and treatment response.
Verhagen, F.H.
core