Results 111 to 120 of about 342,788 (306)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Through Rebel Eyes: Rebel Groups, Human Rights, and Humanitarian Law [PDF]

, 2005
Trafikolyckor är ett globalt folkhälsoproblem som leder till svåra ekonomiska konsekvenser och psykiskt lidande. Ungdomar mellan 15-24 år och framförallt män är en särskilt utsatt grupp av olika anledningar. De har ofta en övertro på sin egen körförmåga,
Jo, Hyeran, Niehaus, John
core   +1 more source

Borophene: Crucial Challenges and the Way Forward

Advanced Science, EarlyView.
This review explores the challenges and progress in borophene research, focusing on synthesis strategies, structural properties, and potential applications. It highlights key experimental breakthroughs, discusses theoretical insights into borophene's unique features, and addresses pathways for overcoming stability and scalability issues.
Zhixuan Li, Jeyaraman Sankar, Prashant Kumar, Ajayan Vinu   +3 more
wiley   +1 more source

REGULILE APLICABILE RECRUTĂRII COPIILOR-SOLDAŢI ÎN DREPTUL INTERNAŢIONAL UMANITAR

Studia Universitatis Moldaviae: Stiinte Sociale, 2009
All members of a society suffer the consequences of armed conflicts in their area. However, the magnitude of these consequences for vulnerable groups, especially children, is often poorly understood.
USM ADMIN
doaj  

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Advanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao, Shan Qiao, Jie Bai, Jingjing Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu   +10 more
wiley   +1 more source

The dead and missing in armed conflict: Protections set out in the judgments of the European and Inter-American Courts of Human Rights

International Review of the Red Cross
In their analyses of specific cases involving armed conflict, the European Court of Human Rights and the Inter-American Court of Human Rights have acted as monitoring bodies for international humanitarian law (IHL) by factoring that body of law into ...
Juana María Ibáñez Rivas
doaj   +1 more source

MELEGROS: Monolithic Elephant‐Inspired Gripper with Optical Sensors

Advanced Science, EarlyView.
MELEGROS is a monolithic, elephant‐inspired soft gripper integrating 3D‐printed optical sensors within a pneumatically actuated lattice. Simulation‐guided design decouples tactile and proprioceptive sensing. Characterized through grasping tests, MELEGROS can reach, scoop, and grasp, showcasing a paradigm where fully embedded sensing and continuous ...
Petr Trunin, Diana Cafiso, Anderson Brazil Nardin, Trevor Exley, Lucia Beccai   +4 more
wiley   +1 more source

Revisiting Enhanced Protection: Implications from a Practical Case Study

Santander Art & Culture Law Review
The 1999 Second Protocol to the Hague Convention for the Protection of Cultural Property in the Event of Armed Conflict (1954) created a new legal framework to improve protection for the world’s most ...
Emma Cunliffe
doaj   +1 more source

The limits of law in a post-Westphalian world: the legal and political status of powerful non-state armed actors—a comparative study of Hezbollah and the Houthis

Frontiers in Political Science
This article investigates the profound challenges posed by powerful, sub-state armed actors to the international legal system and the traditional Westphalian concept of state sovereignty.
Khaled Mohammad Khwaileh
doaj   +1 more source

Multimodal Cross‐Attentive Graph‐Based Framework for Predicting In Vivo Endocrine Disruptors

Advanced Science, EarlyView.
A multimodal cross‐attentive graph neural network integrates molecular graphs with androgen and estrogen adverse outcome pathway (AOP)–anchored in vitro assay signals to predict in vivo endocrine disruption. By fusing information on Tier‐1 AOP logits with chemical structures, the framework achieves high accuracy and provides assay‐traceable ...
Eder Soares de Almeida Santos, Gustavo Felizardo Santos Sandes, Artur Christian Garcia da Silva, Holli‐Joi Martin, Eugene N. Muratov, Rodolpho de Campos Braga, Bruno Junior Neves   +6 more
wiley   +1 more source