Results 51 to 60 of about 2,756,582 (315)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Effectivness of the GnRH analogue deslorelin as a reversible contraceptive in a neotropical primate, the Common Marmoset Callithrix Jacchus (Mammalia: Primates: Callitrichidae)

Journal of Threatened Taxa, 2016
Deslorelin is a synthetic GnRH analogue, which is being used as a contraceptive in animals by acting as a gonadal suppressant.  The product Suprelorin (Virbac, Australia) contains deslorelin as a biocompatible, slow release subcutaneous implant.
Derek A. Rosenfield, P. Viau, C. A. Oliveira, Cristiane Schilbach Pizzutto   +3 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A decline in the incidence of invasive non-typhoidal Salmonella infection in The Gambia temporally associated with a decline in malaria infection. [PDF]

, 2010
BACKGROUND: Malaria is a risk factor for invasive non-typhoidal Salmonella (NTS) infection in children. In the last 10 years, indices of malaria infection in The Gambia have fallen substantially.
Greenwood, Brian M, Tim O'Dempsey, Conway, David J., Bojang Kalifa A., Umberto D'Alessandro, Mackenzie Grant, D'Alessandro Umberto, Ikumapayi Usman N. A., Michael Walther, Kalifa A Bojang, Adegbola, Richard A., Saha, Debasish, Godwin Enwere, Philip C Hill, Serign J Ceesay, Conway David J., Walther, Michael, Usman N A Ikumapayi, Mackenzie, Grant, Greenwood Brian M., Debasish Saha, Tumani Corrah, Corrah, Tumani, Greenwood, Brian M., Hill, Philip C, Brian M Greenwood, Ikumapayi, Usman NA, Adegbola, Richard A, Corrah Tumani, Enwere, Godwin, Walther Michael, Grant Mackenzie, Conway, David J, Hill Philip C., O'Dempsey, Tim, David J Conway, Ceesay, Serign J, Bojang, Kalifa A, David C W Mabey, O'Dempsey Tim, Richard A Adegbola, Hill, Philip C., Judith Satoguina, O'Dempsey, Timothy, Saha Debasish, Bojang, Kalifa A., Mabey David C. W., D'Alessandro, Umberto, Enwere Godwin, Ceesay Serign J., Ikumapayi, Usman N.A., Adegbola Richard A., Mabey, David CW, Satoguina Judith, Mabey, David C.W., Ceesay, Serign J., Satoguina, Judith   +56 more
core   +1 more source

Non-invasive electromagnetic detection of prostate cancer: efficiency analysis

Вестник урологии, 2023
Introduction. Early diagnosis of cancer is one of the most important international strategies. Malignant and healthy tissues differ in the interaction with electromagnetic waves.
M. E. Chaliy, E. V. Afanasyevskaya, A. S. Amirkhanyan, A. A. Strigunov, A. M. Kadysheva, E. V. Kolygina, A. S. Shurygina, A. S. Tivtikyan, A. V. Kadrev, V. K. Dzitiev, D. A. Okhobotov, N. I. Sorokin, A. A. Kamalov   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Emerging Trends in Optical Fiber Biosensing for Non-Invasive Biomedical Analysis

Photonics
Optical fiber biosensors have evolved into powerful tools for non-invasive biomedical analysis. While foundational principles are well-established, recent years have marked a paradigm shift, driven by advancements in nanomaterials, fabrication techniques,
Sajjad Mortazavi, Somayeh Makouei, Karim Abbasian, Sebelan Danishvar   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source