Results 151 to 160 of about 108,821 (296)

Non-invasive therapeutics for neurotrauma: a mechanistic overview

Frontiers in Neurology
Traumatic brain injury is a leading cause of death and a major risk factor for the development of both memory and motor disorders. To date, there are no proven interventions to improve patient outcome after neurotrauma.
James D. O'Leary, Bevan S. Main, Mark P. Burns   +2 more
doaj   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Non-invasive Brain Stimulation in Physical Medicine and Rehabilitation

, 2014
The non-invasive brain stimulation techniques of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have developed considerably over the last 25 years. Recent studies have used these techniques to enhance motor and
Celnik, Pablo A., Hardwick, Robert
core   +1 more source

Safe administration of low frequency rTMS in a patient with depression with recurrent antidepressant-associated hyponatremic seizures

Brain Stimulation, 2020
Milind Vijay Thanki, Sachin Pradeep Baliga, Soumya Parameshwaran, Naren P. Rao, Urvakhsh Meherwan Mehta, Jagadisha Thirthalli   +5 more
doaj   +1 more source

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Non-Invasive Brain Sensing Technologies for Modulation of Neurological Disorders

Biosensors
The non-invasive brain sensing modulation technology field is experiencing rapid development, with new techniques constantly emerging. This study delves into the field of non-invasive brain neuromodulation, a safer and potentially effective approach for ...
Salman Alfihed, Majed Majrashi, Muhammad Ansary, Naif Alshamrani, Shahad H. Albrahim, Abdulrahman Alsolami, Hala A. Alamari, Adnan Zaman, Dhaifallah Almutairi, Abdulaziz Kurdi, Mai M. Alzaydi, Thamer Tabbakh, Faisal Al-Otaibi   +12 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

A Brain-Computer Interface for robotic arm control

, 2011
Lenhardt A. A Brain-Computer Interface for robotic arm control. Bielefeld: Universität Bielefeld; 2011.Brain-Computer Interfaces (BCI) are tools that open a new channel of communication between humans and machines.
Lenhardt, Alexander
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source