Results 141 to 150 of about 1,612,607 (331)

Ecological models at fish community and species level to support effective river restoration

open access: yes, 2013
RESUMEN Los peces nativos son indicadores de la salud de los ecosistemas acuáticos, y se han convertido en un elemento de calidad clave para evaluar el estado ecológico de los ríos.
Olaya Marín, Esther Julia
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Study of Imaging Analysis for Distinguishing Alveolar Collapse From Invasive Lesions in Early‐Stage Lung Adenocarcinoma

open access: yesThoracic Cancer
Background Non‐invasive lung adenocarcinoma may occasionally contain solid benign components, presenting challenges for making an accurate diagnosis using CT (computed tomography).
Shinji Kaneda   +5 more
doaj   +1 more source

[Success and failure predictors of non-invasive ventilation in acute bronchiolitis].

open access: yesAnales de pediatria (Barcelona, Spain : 2003), 2009
The objective was to identify predictive factors for non-invasive ventilation (NIV) failure and to describe its use in bronchiolitis.Prospective observational study that included patients diagnosed with bronchiolitis with a modified Wood's Clinical Asthma Score 5, or oxygen saturation
J, Mayordomo-Colunga   +5 more
openaire   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction

open access: yesAnnals of Noninvasive Electrocardiology
Objective To investigate the correlation between non‐invasive cardiac function monitoring indexes and recent adverse prognosis in patients with STEMI.
Jiayan Xin   +3 more
doaj   +1 more source

Predictors of Successful Testicular Sperm Extraction: A New Era for Men with Non-Obstructive Azoospermia

open access: yesBiomedicines
Background/Objectives: Non-obstructive azoospermia (NOA) is a severe form of male infertility characterized by the absence of sperm in the ejaculate due to impaired spermatogenesis.
Aris Kaltsas   +9 more
doaj   +1 more source

Hyaluronic acid levels predict risk of hepatic encephalopathy and liver-related death in HIV/viral hepatitis coinfected patients [PDF]

open access: yes, 2013
Background: Whereas it is well established that various soluble biomarkers can predict level of liver fibrosis, their ability to predict liver-related clinical outcomes is less clearly established, in particular among HIV/viral hepatitis co-infected ...
Karlsson, Anders   +9 more
core  

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