Results 161 to 170 of about 1,612,607 (331)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Liver stiffness measurement, Doppler ultrasound, and serum non-invasive markers as predictors of varices and variceal bleeding in cirrhotic patients

Egyptian Liver Journal
Background and aims Variceal bleeding is a life-threatening complication of liver cirrhosis, necessitating reliable non-invasive predictors to minimize the use of the more invasive esophagogastroduodenoscopy (EGD).
Waleed Attia Hassan, Reham M. Kemaly, Mostafa A. Sayed, Hanan M. Nafeh   +3 more
doaj   +1 more source

Association between CT features and tumor invasiveness of lung cancer associated with cystic airspace

Heliyon
Background: Lung cancer associated with cystic airspaces is a rare pattern in lung cancer morphology and invasive adenocarcinoma makes the most part of pathological types after resection, of which the prognosis is significantly worse than pre-invasive ...
Hangtian Xi, Yong Zhang, Ning Chang, Dan Qiu, Xiangxiang Chen, Ling Cao, Min Wang, Ying Zhou, Xiaohui Wang, Xiaolong Yan, Hong Yin, Jian Zhang   +11 more
doaj   +1 more source

Non-invasive predictors of prognosis of Asian patients with histopathologically-confirmed lean nonalcoholic fatty liver disease. [PDF]

BMC Gastroenterol, 2020
Iritani S, Akuta N, Kawamura Y, Kajiwara A, Kasuya K, Fujiyama S, Sezaki H, Hosaka T, Kobayashi M, Kobayashi M, Saito S, Suzuki F, Arase Y, Ikeda K, Suzuki Y, Kumada H.   +15 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Non-invasive simple predictors of biliary atresia in cholestatic infants – A preliminary report

Pediatrics & Neonatology
Biliary atresia (BA) and other cholestatic liver diseases of early infancy share many similar clinical manifestations. We intended to investigate easy and popular non-invasive parameters to assist the differential diagnosis of BA among cholestatic infants.We enrolled 145 consecutive cholestatic infants (43.03 ± 2.00 days) who underwent cholestatic ...
Yu-Hsueh Hsiao, Wei-Li Hung, Yao-Jong Yang, Fang-Ting Lu, Fang-Min Liao, Cheng-Yu Chen, Jia-Feng Wu   +6 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Development of a Type 2 Diabetes Prediction Model Using Specific Health Checkup Data and Extraction of Predictive Factors

Bioengineering
Background: Specific health checkups in Japan aim to prevent and detect non-communicable diseases (NCDs). Lifestyle information and non-invasive measurements obtained during these checkups are valuable for population health monitoring.
Kenichiro Shimai, Kazuki Ohashi, Teppei Suzuki, Ryota Konno, Ryuichiro Ueda, Masami Mukai, Katsuhiko Ogasawara   +6 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Machine-learning classification of non-native plant status in the Brazilian dry forest, Caatinga

Discover Conservation
Biological invasions are a major driver of global biodiversity loss, yet predictive frameworks remain underdeveloped, particularly in underexplored ecosystems such as the Caatinga dry forest in Brazil.
Thieres Santos Almeida, Daniel de Paiva Silva, Pablo A. Martinez, Anny Bianca Santos Cruz, Daniel da Paixão Menezes, Eduardo Vinícius da S. Oliveira, Sidney F. Gouveia   +6 more
doaj   +1 more source