Results 161 to 170 of about 42,912 (201)

Non‐invasive prenatal testing 10 years on

Prenatal Diagnosis, 2021
This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
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Non-invasive prenatal testing for Down syndrome

Seminars in Fetal and Neonatal Medicine, 2014
Prenatal screening and diagnosis of Down syndrome and other major aneuploidies may be transformed following the identification of cell-free fetal DNA in maternal plasma at the end of the last millennium. Next generation sequencing has enabled the development of tests that accurately predict the presence of fetal trisomies by analysis of cell-free DNA ...
Philip, Twiss, Melissa, Hill, Rebecca, Daley, Lyn S, Chitty   +3 more
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Physician Liability and Non-Invasive Prenatal Testing

Journal of Obstetrics and Gynaecology Canada, 2014
Although non-invasive prenatal testing (NIPT) marks a notable development in the field of prenatal genetic testing, there are some physician liability considerations raised by this technology. As NIPT is still emerging as the standard of care and is just starting to receive provincial funding, the question arises of whether physicians are obligated to ...
Maeghan, Toews, Timothy, Caulfield
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Insurance and geographic variations in non‐invasive prenatal testing

Prenatal Diagnosis, 2022
Key pointsWhat is already known about this topic? Single‐site studies suggest racial, ethnic, and insurance disparities in use of Non‐invasive prenatal testing (NIPT). Population‐level research from outside the U.S. highlights significant geographic variations in NIPT uptake. What does this study add?
Jacqueline Ellison, Catharine Wang, Christina Yarrington, Philip Connors, Amresh Hanchate   +4 more
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Sex discordance identification following non‐invasive prenatal testing

Prenatal Diagnosis, 2017
AbstractObjectiveThe objectives of this study were to characterise genotype‐phenotype discordance identified in the routine clinical setting and to explore the associated diagnostic and counselling challenges.MethodCases were derived from a cohort of pregnant women who attended a multisite specialist prenatal screening and ultrasound service for non ...
Ebony J. Richardson, Fergus P. Scott, Andrew C. McLennan   +2 more
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Non-invasive prenatal paternity testing from maternal blood

International Journal of Legal Medicine, 2008
Prenatal paternity analysis can be performed only after invasive sampling of chorionic villi or amnionic fluid. Aiming to enable noninvasive paternity testing, we attempted to amplify fetal alleles from maternal plasma. Cell-free DNA was isolated from plasma of 20 pregnant women and amplified with ampFLSTR Identifiler and ampFLSTR Yfiler kits ...
Marjanović, Damir, Džijan, Snježana, Wagner Kostadinović, Jasenka, Lauc, Gordan   +3 more
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Realising the promise of non-invasive prenatal testing

BMJ, 2015
It should transform the quality of antenatal care The presence in maternal plasma of cell-free fetal DNA, which is pregnancy specific1 and represents the whole of the fetal genome,2 offers enormous promise for the development of a wide range of prenatal genetic tests.
Lyn S, Chitty, Mark, Kroese
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Non-Invasive Prenatal Testing: Ethics and Policy Considerations

Journal of Obstetrics and Gynaecology Canada, 2014
New technologies analyzing fetal DNA in maternal blood have led to the wide commercial availability of non-invasive prenatal testing (NIPT). We present here for clinicians the ethical and policy issues related to an emerging practice option. Although NIPT presents opportunities for pregnant women, particularly women who are at increased risk of having ...
Meredith, Vanstone, Carol, King, Barbra, de Vrijer, Jeff, Nisker   +3 more
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Non-invasive prenatal testing.

Australian family physician, 2018
Non-invasive prenatal testing (NIPT), also known as cell-free DNA testing and non-invasive prenatal screening (NIPS), is an important addition to the range of screening tests for fetal chromosomal abnormalities. For trisomy 21 in particular, NIPT is superior to other screening modalities.
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How ‘non-invasive’ is non-invasive prenatal testing?

Journal of Medical Ethics
The invasiveness of a medical intervention is considered to be morally important and can have a significant influence on acceptability and uptake. De Marco et al propose a novel account of the invasiveness of medical interventions that better reflects the common understanding of the term.
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