Results 41 to 50 of about 12,620,879 (241)

Non-Invasive Prenatal Testing beyond Trisomies

Journal of Medicine and Life, 2019
The last decade has seen incredible advances in the genetic era, in next-generation sequencing of cell-free DNA in the maternal plasma, detecting abnormal fetal chromosomes. Non-invasive prenatal testing (NIPT) has showed increased sensitivity and specificity for Down syndrome superior to any other screening test.
Suciu, Ioan Dumitru, Toader, Oana Daniela, Galeva, Slavyana, Pop, Lucian   +3 more
openaire   +2 more sources

False negativity for trisomy 18 in non-invasive prenatal testing: A case report

Case Reports in Women's Health
False-negative results in non-invasive prenatal testing are rare but clinically significant, particularly in the presence of biological factors such as feto-placental mosaicism.
Natália Andová, Vanda Repiská, Petra Priščáková, Lajos Gergely, Michaela Hýblová, Gabriel Minárik   +5 more
doaj   +1 more source

Decision-making process about prenatal genetic screening: how deeply do moms-to-be want to know from Non-Invasive Prenatal Testing?

BMC Pregnancy and Childbirth, 2023
Background Prenatal information may be obtained through invasive diagnostic procedures and non-invasive screening procedures. Several psychological factors are involved in the decision to undergo a non-invasive prenatal testing (NIPT) but little is known
Serena Oliveri, Giulia Ongaro, Ilaria Cutica, Giulia Menicucci, Debora Belperio, Francesca Spinella, Gabriella Pravettoni   +6 more
doaj   +1 more source

Non-invasive Prenatal Testing for Fetal Whole Genome Sequencing: An Interpretive Critical Review of the Ethical, Legal, Social, and Policy Implications

Canadian Journal of Bioethics, 2022
Introduction: Non-invasive prenatal testing (NIPT) allows for genetic testing of a fetus through the analysis of cell-free DNA from the mother’s plasma.
Hazar Haidar, Renata Iskander
doaj   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Recent trends in prenatal genetic screening and testing [version 1; peer review: 2 approved]

F1000Research, 2019
Prenatal testing in recent years has been moving toward non-invasive methods to determine the fetal risk for genetic disorders without incurring the risk of miscarriage.
Ondrej Pös, Jaroslav Budiš, Tomáš Szemes   +2 more
doaj   +1 more source

Non-invasive prenatal paternity testing using mini-STR-based next-generation sequencing: a pilot study

Journal of Laboratory Medicine, 2022
To assess the efficacy of a mini-STR-based next-generation sequencing (NGS) method for non-invasive prenatal paternity testing (NIPPT).
Song Wenqian, Xiao Nan, Zhou Shihang, Yu Weijian, Wang Ni, Shao Linnan, Liang Xiaohua   +6 more
doaj   +1 more source

Prenatal testing - diagnostic possibilities in the 21st century with special emphasis on the diagnosis of genetic defects and heart defects

Journal of Education, Health and Sport, 2023
Introduction: Prenatal diagnosis is a branch of medicine that deals with the detection of possible genetic and developmental abnormalities at the fetal life stage.
Grzegorz Tarsa, Rami Ben Rhaiem, Katarzyna Sudelska, Zuzanna Sawińska, Przemysław Kępka, Aleksandra Łokczewska-Bojar, Daria Kuziemkowska, Jan Kuźma, Magdalena Skotalczyk, Anna Łącka-Majcher   +9 more
doaj   +1 more source

Non-invasive foetal sexing : medical test or a new tool for sex selection? [PDF]

, 2011
Recent scientific developments in prenatal testing, based on foetal DNA in maternal blood, now allow non-invasive foetal sexing early in pregnancies at risk of a sex-linked disorder. In such cases, these novel non-invasive tests can improve prenatal care
Szczepura, Ala, Osipenko, Leeza
core  

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source