Inconsistency between non-invasive prenatal testing (NIPT) and conventional prenatal diagnosis due to confined placental and fetal mosaicism: Two case reports [PDF]
Frontiers in Medicine, 2022 We aimed to identify the causes of inconsistent results between non-invasive prenatal testing (NIPT) and invasive testing methods for trisomy 21. In the first case, NIPT was performed at 11 weeks of pregnancy, and the result showed a high risk of trisomy
Kyung Min Kang +13 more
doaj +2 more sources
Non-Invasive Prenatal Testing (NIPT): A Paradigm Shift in Prenatal Care [PDF]
International Journal of Preventive MedicinePrenatal screening has undergone a profound transformation with the emergence of Non-Invasive Prenatal Testing (NIPT), a technology that analyzes cell-free fetal DNA (cffDNA) in maternal blood to detect common chromosomal abnormalities.
Ram K. Garg +3 more
doaj +2 more sources
Challenges and clinical implications of discordant non-invasive prenatal testing results: insights from two case studies [PDF]
Folia MedicaNon-invasive prenatal testing (NIPT) has transformed prenatal screening, offering high sensitivity and specificity in the detection of common fetal aneuploidies.
Slavyana Galeva +2 more
doaj +4 more sources
A new era in prenatal care: non-invasive prenatal testing in Switzerland
Swiss Medical Weekly, 2014 QUESTIONS UNDER STUDY: Prenatal care has been significantly influenced by the introduction of non-invasive prenatal testing (NIPT) for aneuploidies in 2012. The aim of this study was to describe the current impact of NIPT on prenatal care.
Gwendolin Manegold-Brauer +6 more
doaj +2 more sources
Mainstreaming genetics into Italian prenatal care: exploring the future implementation of non-invasive prenatal testing (NIPT) in the Italian National Healthcare System using stakeholder interviews [PDF]
BMJ Public HealthIntroduction Non-invasive prenatal testing (NIPT) has revolutionised the way prenatal testing is performed globally. Italy is one of the European countries considering incorporating NIPT nationwide into the publicly funded healthcare system.
Giulia Sesa +3 more
doaj +2 more sources
Investigational Management for a Positive NIPT Result - Case Report [PDF]
Modern MedicineNon-invasive prenatal testing (NIPT), since its introduction in 2011, has revolutionized prenatal screening, becoming widely used globally and replacing traditional screening methods in developed countries.
Elena Evelina STOICA +3 more
doaj +2 more sources
Journal of Obstetrics and Gynaecology, 2023 Background Non-invasive prenatal testing (NIPT) has been widely adopted as an approach for foetal aneuploidy screening. This study was to evaluate the performance of NIPT for foetal T21 detection in subgroups of pregnancies and the correlation between Z ...
Feng Suo +11 more
doaj +2 more sources
Modelling the cost-effectiveness of non-invasive prenatal testing in the English sickle cell and thalassaemia screening pathway [PDF]
Diagnostic and Prognostic ResearchBackground Sickle cell disease (SCD) and thalassaemia are inherited conditions causing chronic anaemia, increased infection risk and multi-organ failure.
Vittoria Vardanega +10 more
doaj +2 more sources
Regulating non-invasive prenatal testing (NIPT) for fetal sex determination. [PDF]
Med Law Rev, 2023 Non-invasive prenatal testing (NIPT) can be used to determine the chromosomal sex of the fetus at an early stage in a pregnancy. The use of NIPT for fetal sex determination raises concerns about potential selective termination of pregnancy by prospective
Taylor-Sands M +2 more
europepmc +2 more sources
A Fetal Fraction Optimized 106-Plex Digital PCR Assay for Non-Invasive Prenatal Testing of Fetal Trisomy [PDF]
DiagnosticsBackground/Objectives: Non-invasive prenatal testing (NIPT) for fetal aneuploidy requires accurate trisomy detection together with reliable fetal fraction assessment.
Songchang Chen +8 more
doaj +2 more sources