Results 21 to 30 of about 12,655,449 (158)

Performance of expanded non-invasive prenatal testing for fetal aneuploidies and copy number variations: A prospective study from a single center in Jiangxi province, China

Frontiers in Genetics, 2023
To evaluate the performance of expanded non-invasive prenatal testing (expanded noninvasive prenatal testing, NIPT-Plus) in screening for fetal chromosomal abnormalities includes aneuploidies and copy number variations, a total of 23,116 pregnant women ...
Yongyi Zou, Yongyi Zou, Chuanxin Feng, Chuanxin Feng, Jiawei Qin, Jiawei Qin, Xinrong Wang, Tingting Huang, Tingting Huang, Yan Yang, Yan Yang, Kang Xie, Kang Xie, Huizhen Yuan, Huizhen Yuan, Shuhui Huang, Shuhui Huang, Bicheng Yang, Bicheng Yang, Wan Lu, Wan Lu, Yanqiu Liu, Yanqiu Liu   +22 more
doaj   +1 more source

Analysis of the accuracy of Z-scores of non-invasive prenatal testing for fetal Trisomies 13, 18, and 21 that employs the ion proton semiconductor sequencing platform

Molecular Cytogenetics, 2018
Background Non-invasive prenatal testing (NIPT) is frequently being used to screen for trisomies 13, 18 and 21 for prenatal diagnosis. However, NIPT performs poorly when compared with invasive testing and thus should not be used to diagnose trisomies ...
Yuan Tian, Linlin Zhang, Weifang Tian, Jinshuang Gao, Liting Jia, Shihong Cui   +5 more
doaj   +1 more source

Recent trends in prenatal genetic screening and testing [version 1; peer review: 2 approved]

F1000Research, 2019
Prenatal testing in recent years has been moving toward non-invasive methods to determine the fetal risk for genetic disorders without incurring the risk of miscarriage.
Ondrej Pös, Jaroslav Budiš, Tomáš Szemes   +2 more
doaj   +1 more source

An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population. [PDF]

PLoS ONE, 2015
Analyze the economic value of replacing conventional fetal aneuploidy screening approaches with non-invasive prenatal testing (NIPT) in the general pregnancy population.Using decision-analysis modeling, we compared conventional screening to NIPT with ...
Peter Benn, Kirsten J Curnow, Steven Chapman, Steven N Michalopoulos, John Hornberger, Matthew Rabinowitz   +5 more
doaj   +1 more source

Non-Invasive Prenatal Testing and Confined Placental Mosaicism

, 2023
My research subject is non-invasive prenatal testing (NIPT), a screening offered in pregnancy to detect fetal chromosome anomalies. In my research, we investigate whether false-positive NIPT results may be attributable to genetic anomalies confined to ...
Yvette Raymond (13012777)
core   +1 more source

Patient Perception of Negative Noninvasive Prenatal Testing Results

American Journal of Perinatology Reports, 2016
Objective To determine patient perception of residual risk after receiving a negative non-invasive prenatal testing result. Introduction Recent technological advances have yielded a new method of prenatal screening, non-invasive prenatal ...
A. Theresa Wittman, S. Shahrukh Hashmi, Hector Mendez-Figueroa, Salma Nassef, Blair Stevens, Claire N. Singletary   +5 more
doaj   +1 more source

Non-invasive prenatal test uptake in socioeconomically disadvantaged neighborhoods [PDF]

, 2021
Objective: Non-Invasive Prenatal Testing (NIPT) is increasingly being implemented worldwide. In public health programs, equitable access to healthcare is a fundamental principle which also applies to fetal aneuploidy screening. However, the out-of-pocket
Dutch NIPT Consortium
core  

Investigational Management for a Positive NIPT Result - Case Report [PDF]

Modern Medicine
Non-invasive prenatal testing (NIPT), since its introduction in 2011, has revolutionized prenatal screening, becoming widely used globally and replacing traditional screening methods in developed countries.
Elena Evelina STOICA, Laurentiu Camil BOHILTEA, Delia-Maria Gradinaru-FOMETESCU, Monica Mihaela CIRSTOIU   +3 more
doaj   +1 more source

Discordant performances of non-invasive prenatal testing for foetal trisomy 21 screening in subgroups of pregnancies

Journal of Obstetrics and Gynaecology, 2023
Background Non-invasive prenatal testing (NIPT) has been widely adopted as an approach for foetal aneuploidy screening. This study was to evaluate the performance of NIPT for foetal T21 detection in subgroups of pregnancies and the correlation between Z ...
Feng Suo, Yi Wang, Na Wang, Yawen Wang, Mingming Liao, Jingjing Wang, Chuanxia Wang, Yan Zhang, Man Zhang, Chu Zhang, Maosheng Gu, Lingshan Gou   +11 more
doaj   +1 more source

Whole genome non-invasive prenatal testing in prenatal screening algorithm: clinical experience from 12,700 pregnancies

BMC Pregnancy and Childbirth, 2022
Background A fast adoption of a non–invasive prenatal testing (NIPT) in clinical practice is a global tendency last years. Firstly, in Russia according a new regulation it was possible to perform a widescale testing of pregnant women in chromosomal ...
Elena E. Baranova, Olesya V. Sagaydak, Alexandra M. Galaktionova, Ekaterina S. Kuznetsova, Madina T. Kaplanova, Maria V. Makarova, Maxim S. Belenikin, Anton S. Olenev, Ekaterina N. Songolova   +8 more
doaj   +1 more source