Patient experience with non-invasive prenatal testing (NIPT) as a primary screen for aneuploidy in the Netherlands. [PDF]
BMC Pregnancy Childbirth, 2022 Abstract Background Non-invasive prenatal testing (NIPT) as a screening method for trisomy 21 and other chromosomal abnormalities has been adopted widely across the globe. However, while many clinical validation studies have been performed, less is known regarding the patient experience with NIPT. This study explored how
Kristalijn SA +5 more
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Non-invasive prenatal testing (NIPT): a better option for patients [PDF]
Molecular Cytogenetics, 2014 At present there are two methods to determine the chromosome health of unborn fetus in pregnant women. One is through maternal serum screening that is considered as simple but less sensitive method and the second options involves invasive methods like amniocentesis or chorionic villus sampling (CVS) for women who are found to be positive in maternal ...
Ashish Fauzdar
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Inconsistency between non-invasive prenatal testing (NIPT) and conventional prenatal diagnosis due to confined placental and fetal mosaicism: Two case reports [PDF]
Frontiers in Medicine, 2022 We aimed to identify the causes of inconsistent results between non-invasive prenatal testing (NIPT) and invasive testing methods for trisomy 21. In the first case, NIPT was performed at 11 weeks of pregnancy, and the result showed a high risk of trisomy
Kyung Min Kang +13 more
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Non-invasive prenatal testing (NIPT) and pregnant women's views on good motherhood: a qualitative study. [PDF]
Eur J Hum Genet, 2022 Women's views on responsible motherhood influence decision-making regarding participation in prenatal screening. Previous studies showed that the probabilistic nature of the first-trimester combined test and the potential requirement for subsequent invasive diagnostics serve as legitimate reasons for women to exclude prenatal screening from their moral
Garcia E +6 more
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Adoption of a non-invasive prenatal test (NIPT) in prenatal screening in Moscow: first results [PDF]
Russian Open Medical Journal, 2021 The objective — To assess the effectiveness of including NIPT in the structure of prenatal diagnostics in Moscow. Material and Methods — Totally 5,181 pregnancies undergoing screening for fetal trisomy using NIPT during the period from 01.04.2020 to 30.09.2020 in Russia. According to the results of biochemical blood test, the patients were divided into
А.С. Оленев +7 more
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Non-invasive prenatal testing (NIPT): does the practice discriminate against persons with disabilities? [PDF]
Journal of Perinatal Medicine, 2021 Abstract The most well-known goal of non-invasive prenatal testing (NIPT) is still to determine whether or not a fetus has trisomy 21. Since women often terminate the pregnancy upon a positive result, there is concern that the use of NIPT contributes to discrimination against persons with disabilities.
Annette Dufner
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Rethinking counselling in prenatal screening: An ethical analysis of informed consent in the context of non-invasive prenatal testing (NIPT). [PDF]
Bioethics, 2020 AbstractInformed consent is a key condition for prenatal screening programmes to reach their aim of promoting reproductive autonomy. Reaching this aim is currently being challenged with the introduction of non‐invasive prenatal testing (NIPT) in first‐trimester prenatal screening programmes: amongst others its procedural ease—it only requires a blood ...
Kater-Kuipers A +3 more
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NIPTRIC: an online tool for clinical interpretation of non-invasive prenatal testing (NIPT) results. [PDF]
Sci Rep, 2016 AbstractTo properly interpret the result of a pregnant woman’s non-invasive prenatal test (NIPT), her a priori risk must be taken into account in order to obtain her personalised a posteriori risk (PPR), which more accurately expresses her true likelihood of carrying a foetus with trisomy.
Sikkema-Raddatz B +11 more
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First trimester screening with biochemical markers and ultrasound in relation to non-invasive prenatal testing (NIPT) [PDF]
Journal of Perinatal Medicine, 2021 Abstract Non-invasive prenatal testing (NIPT) is often erroneously received as a diagnostic procedure due to its high discriminatory power in the field of fetal trisomy 21 diagnosis (wording: “NIPT replaces amniocentesis”). Already a look at the methodology of NIPT (statistical gene dose comparison of a primarily maternofetal DNA mixture
Alexander Scharf
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Retrospective Results of Our Non-Invasive Prenatal Test (NIPT) Experience
Ege Tıp DergisiAim: Non-invasive prenatal test (NIPT) has become widespread over the years with higher probabilities of detection and fewer false positives with regard to traditionally used screening techniques. We aimed to document the experience of introducing this kind of equipment intoiclinical practice, evaluate its impact on the detection of fetal-aneuploidies,
Ufuk Atlıhan +5 more
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