Results 21 to 30 of about 4,684 (217)

Implementation of non-invasive prenatal testing by semiconductor sequencing in a genetic laboratory [PDF]

, 2016
Objectives: To implement non-invasive prenatal testing (NIPT) for fetal aneuploidies with semiconductor sequencing in an academic cytogenomic laboratory and to evaluate the first 15-month experience on clinical samples.
De Smet, Matthias, Dheedene, Annelies, Grisart, Bernard, Janssens, Sandra, Menten, Björn, Sante, Tom, Vanbellinghen, Jean-François, Vergult, Sarah   +7 more
core   +2 more sources

Analysis of the accuracy of Z-scores of non-invasive prenatal testing for fetal Trisomies 13, 18, and 21 that employs the ion proton semiconductor sequencing platform

Molecular Cytogenetics, 2018
Background Non-invasive prenatal testing (NIPT) is frequently being used to screen for trisomies 13, 18 and 21 for prenatal diagnosis. However, NIPT performs poorly when compared with invasive testing and thus should not be used to diagnose trisomies ...
Yuan Tian, Linlin Zhang, Weifang Tian, Jinshuang Gao, Liting Jia, Shihong Cui   +5 more
doaj   +1 more source

A new era in prenatal care: non-invasive prenatal testing in Switzerland

Swiss Medical Weekly, 2014
QUESTIONS UNDER STUDY: Prenatal care has been significantly influenced by the introduction of non-invasive prenatal testing (NIPT) for aneuploidies in 2012. The aim of this study was to describe the current impact of NIPT on prenatal care.
Gwendolin Manegold-Brauer, Anjeung Kang Bellin, Sinuhe Hahn, Christian De Geyter, Johanna Buechel, Irene Hoesli, Olav Lapaire   +6 more
doaj   +1 more source

Trial by Dutch laboratories for evaluation of non-invasive prenatal testing. Part I—clinical impact [PDF]

, 2016
Objective: To evaluate the clinical impact of nationwide implementation of genome-wide non-invasive prenatal testing (NIPT) in pregnancies at increased risk for fetal trisomies 21, 18 and 13 (TRIDENT study).
Bax, C.J. (Caroline), Bekker, M.N. (Mireille), Bilardo, C.M. (Caterina Maddalena), Boon, E.M.J. (Elles ), Coumans, A. (Audrey), Faas, B.H.W. (Brigitte), Galjaard, R-J.H. (Robert-Jan), Go, A.T.J.I. (Attie), Henneman, L. (Lidewij), Huijsdens-van Amsterdam, K. (Karin), Macville, M.V.E. (Merryn), Oepkes, D., Page-Christiaens, G.C.L. (G. C. Lieve), Pajkrt, E. (Eva), Schuring-Blom, G.H. (Heleen), Sistermans, E.A. (Erik), Suijkerbuijk, R. (Ron), Van Opstal, A.R.M. (Diane), Verweij, E.J.J. (E. J. Joanne), Weiss, M.M. (Marjan M.)   +19 more
core   +1 more source

Recent trends in prenatal genetic screening and testing [version 1; peer review: 2 approved]

F1000Research, 2019
Prenatal testing in recent years has been moving toward non-invasive methods to determine the fetal risk for genetic disorders without incurring the risk of miscarriage.
Ondrej Pös, Jaroslav Budiš, Tomáš Szemes   +2 more
doaj   +1 more source

An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population. [PDF]

PLoS ONE, 2015
Analyze the economic value of replacing conventional fetal aneuploidy screening approaches with non-invasive prenatal testing (NIPT) in the general pregnancy population.Using decision-analysis modeling, we compared conventional screening to NIPT with ...
Peter Benn, Kirsten J Curnow, Steven Chapman, Steven N Michalopoulos, John Hornberger, Matthew Rabinowitz   +5 more
doaj   +1 more source

A two-year experience of non-invasive prenatal testing (NIPT) at an urban tertiary medical center in South Korea

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To report our experience of implementing non-invasive prenatal testing (NIPT) in a tertiary urban academic medical center in South Korea.
Joseph J. Noh, Hyun Mee Ryu, Soo-young Oh, Suk-Joo Choi, Cheong-Rae Roh, Jong-Hwa Kim   +5 more
doaj   +1 more source

For your interest?:The ethical acceptability of using non-invasive prenatal testing to test 'purely for information' [PDF]

, 2014
Non-invasive prenatal testing (NIPT) is an emerging form of prenatal genetic testing that provides information about the genetic constitution of a foetus without the risk of pregnancy loss as a direct result of the test procedure.
Clarke, Angus J, Deans, Zuzana, Newson, Ainsley J   +2 more
core   +3 more sources

Uptake, outcomes, and costs of implementing non-invasive prenatal testing for Down's syndrome into NHS maternity care: prospective cohort study in eight diverse maternity units. [PDF]

, 2016
OBJECTIVE:  To investigate the benefits and costs of implementing non-invasive prenatal testing (NIPT) for Down's syndrome into the NHS maternity care pathway. DESIGN:  Prospective cohort study.
Cameron, L, Chitty, LS, Daley, R, Fisher, J, Hill, M, Howarth, A, Jenkins, L, Kroese, M, Lewis, C, Mason, S, McEwan, A, McKay, F, Morris, S, Verhoef, TI, Wright, D   +14 more
core   +1 more source

The implementation of non-invasive prenatal testing (NIPT) in the Netherlands

Journal of Perinatal Medicine, 2021
Abstract In the Netherlands prenatal screening is offered as a mean to increase reproductive choices of couples. All women are counseled on the existing options by trained midwives. The government puts a great emphasis on informed choice and on womens’ opinions and reactions to screenings options. Since 2017 non-invasive prenatal testing
openaire   +4 more sources