Investigational Management for a Positive NIPT Result - Case Report [PDF]
Modern MedicineNon-invasive prenatal testing (NIPT), since its introduction in 2011, has revolutionized prenatal screening, becoming widely used globally and replacing traditional screening methods in developed countries.
Elena Evelina STOICA +3 more
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Retrospective Results of Our Non-Invasive Prenatal Test (NIPT) Experience
Ege Tıp DergisiAim: Non-invasive prenatal test (NIPT) has become widespread over the years with higher probabilities of detection and fewer false positives with regard to traditionally used screening techniques. We aimed to document the experience of introducing this kind of equipment intoiclinical practice, evaluate its impact on the detection of fetal-aneuploidies,
Ufuk Atlıhan +5 more
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Strategies to Detect Chromosomal Anomalies Not Identified by NIPT. [PDF]
Prenat DiagnABSTRACT Introduction Genome‐wide non‐invasive prenatal testing (gwNIPT) has screening limitations for detectable chromosomal conditions and cannot detect microdeletions/microduplications (MD) or triploidy. Thickened nuchal translucency (NT) only detects around 10% of these cases. Methods A 4‐year retrospective study of singleton pregnancies undergoing
Scott F +4 more
europepmc +2 more sources
Diagnosis for choroideremia in a large Chinese pedigree by next‑generation sequencing (NGS) and non‑invasive prenatal testing (NIPT). [PDF]
Mol Med Rep, 2017 To develop an effective strategy to isolate and use cell-free fetal DNA (cffDNA) for the combined use of next-generation sequencing (NGS) for diagnosing choroideremia and non-invasive prenatal testing (NIPT) for Y chromosome determination, a large ...
Zhu L +9 more
europepmc +2 more sources
Non-invasive prenatal testing (NIPT): a call for change in reporting practices
McGill Journal of MedicineThe use of non-invasive prenatal testing (NIPT) technology has revolutionized the practice of prenatal screening. The assay’s validity and reliability have been demonstrated in both low- and high-risk pregnancies.
Samuel Wilson, Jacques Balayla
doaj +2 more sources
Obstetric professionals’ perceptions of non-invasive prenatal testing for Down syndrome: clinical usefulness compared with existing tests and ethical implications [PDF]
BMC Pregnancy and Childbirth, 2017 Background While non-invasive prenatal testing (NIPT) for fetal aneuploidy is commercially available in many countries, little is known about how obstetric professionals in non-Western populations perceive the clinical usefulness of NIPT in comparison ...
Olivia Miu Yung Ngan +4 more
doaj +4 more sources
The Evolution of Prenatal Diagnosis from Invasive Procedures to Non-invasive Prenatal Testing (NIPT) [PDF]
Journal of Medical Diagnostic Methods, 2014 Panagiotis Papanastasopoulos
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Towards a Responsible Implementation of NIPT as a First-Tier Test in Canada: Decision-Makers' Perspectives. [PDF]
Prenat DiagnABSTRACT Objective To explore decision makers' perspectives on the conditions for a responsible implementation of non‐invasive prenatal testing (NIPT) as a first‐tier test in Canadian provinces' healthcare systems. Method A qualitative study was conducted with 16 Canadian decision makers who were interviewed between February 2021 and July 2022.
Roy MC +4 more
europepmc +2 more sources
Termination of Pregnancy After NonInvasive Prenatal Testing (NIPT): Ethical Considerations [PDF]
, 2018 This article explores the Nuffield Council on Bioethics’ recent report about non-invasive prenatal testing. Given that such testing is likely to become the norm, it is important to question whether there should be some ethical parameters regarding its ...
Hull, Richard, Shakespeare, Tom
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Counseling for non‐invasive prenatal testing (NIPT): what pregnant women may want to know [PDF]
Ultrasound in Obstetrics & Gynecology, 2014 Sequencing of cell-free fetal and maternal DNA fragments (cfDNA) in maternal plasma can be used to test for fetal chromosomal abnormalities. In particular, prediction of the presence or absence of fetal trisomy 21, the most common fetal chromosomal ...
D. Oepkes +14 more
semanticscholar +7 more sources