Results 71 to 80 of about 8,134 (208)

Accuracy of non-invasive prenatal testing using cell-free DNA for detection of Down, Edwards and Patau syndromes : a systematic review and meta-analysis [PDF]

, 2016
Objective: To measure test accuracy of non-invasive prenatal testing (NIPT) for Down, Edwards and Patau syndromes using cell-free fetal DNA and identify factors affecting accuracy.
Agbebiyi, Adeola, Clarke, Aileen, Clarke, Angus, Freeman, Karoline, Geppert, Julia, Madan, Jason, Quenby, Siobhan, Taylor-Phillips, Sian, Uthman, Olalekan A.   +8 more
core   +2 more sources

Etiske utfordringer med non-invasive prenatale tester (NIPT)

Etikk i Praksis: Nordic Journal of Applied Ethics, 2014
Analyser av cellefritt DNA fra foster i gravide kvinners blod gir nye muligheter innen fosterdiagnostikk: Testene er bedre enn eksisterende tester, de reduserer risikoen og er billigere.
Bjørn Hofmann
doaj   +1 more source

Evaluation of non-invasive prenatal testing (NIPT) for aneuploidy in an NHS setting: a reliable accurate prenatal non-invasive diagnosis (RAPID) protocol

BMC Pregnancy and Childbirth, 2014
BackgroundNon-invasive prenatal testing (NIPT) for aneuploidies is now available through commercial companies in many countries, including through private practice in the United Kingdom (UK).
M. Hill, D. Wright, R. Daley, C. Lewis, Fiona McKay, S. Mason, N. Lench, A. Howarth, Christopher Boustred, K. Lo, V. Plagnol, K. Spencer, J. Fisher, M. Kroese, S. Morris, L. Chitty   +15 more
semanticscholar   +1 more source

High-throughput non-invasive prenatal testing for fetal rhesus D status in RhD-negative women not known to be sensitised to the RhD antigen : a systematic review and economic evaluation [PDF]

, 2018
Background: High-throughput non-invasive prenatal testing (NIPT) for fetal rhesus (D antigen) (RhD) status could avoid unnecessary treatment with routine anti-D immunoglobulin for RhD-negative women carrying a RhD-negative fetus, although this may lead ...
Griffin, Susan, Harden, Melissa, Llewellyn, Alexis, Palmer, Stephen, Saramago, Pedro, Simmonds, Mark, Walker, Ruth, Yang, Huiqin   +7 more
core   +1 more source

Decision-making about non-invasive prenatal testing: women’s moral reasoning in the absence of a risk of miscarriage in Germany

New Genetics and Society, 2021
This paper examines women’s experiences with decision-making about non-invasive prenatal testing (NIPT). Such tests offer knowledge about chromosomal disorders early in pregnancy, without the risk of miscarriage associated with invasive procedures such ...
Stefan Reinsch, Anika König, Christoph Rehmann-Sutter   +2 more
doaj   +1 more source

Effect of non-invasive prenatal testing as a contingent approach on the indications for invasive prenatal diagnosis and prenatal detection rate of Down's syndrome [PDF]

, 2016
published_or_final_versio
Chan, KY, Kan, SYA, Kou, KOT, Kwok, SL, Leung, KY, Poon, CF, Tang, MHY   +6 more
core   +1 more source

Targeted capture enrichment followed by NGS: development and validation of a single comprehensive NIPT for chromosomal aneuploidies, microdeletion syndromes and monogenic diseases

Molecular Cytogenetics, 2019
Background Non-invasive prenatal testing (NIPT) has been widely adopted for the detection of fetal aneuploidies and microdeletion syndromes, nevertheless, limited clinical utilization has been reported for the non-invasive prenatal screening of monogenic
George Koumbaris, Achilleas Achilleos, Michalis Nicolaou, Charalambos Loizides, Kyriakos Tsangaras, Elena Kypri, Petros Mina, Carolina Sismani, Voula Velissariou, Georgia Christopoulou, Pantelis Constantoulakis, Emmanouil Manolakos, Ioannis Papoulidis, Danai Stambouli, Marios Ioannides, Philippos Patsalis   +15 more
doaj   +1 more source

Comparison of two high-throughput semiconductor chip sequencing platforms in noninvasive prenatal testing for Down syndrome in early pregnancy [PDF]

, 2016
Background: Noninvasive prenatal testing (NIPT) to detect fetal aneuploidy using next-generation sequencing on ion semiconductor platforms has become common. There are several sequencers that can generate sufficient DNA reads for NIPT.
A Fortuny, A Tabor, AB Sparks, B Langmead, BF Crandall, Byung Chul Kim, C Liao, CJ McNamara, DW Bianchi, E Wang, FR Grati, G Ashoor, GE Palomaki, GP Henry, H Li, Hee Jae Joo, HeeJung Jung, Hongliang Chen, Hwanjong Kwak, Hyungsik Chu, JeongSub Kwon, JF Boland, Jong Bhak, K Song, KC Chan, KH Nicolaides, Kyudong Han, M Ehrich, M Smid, MA Quail, ME Norton, Min Gyun Kim, MJKT Barch, N Vrachnis, P Benn, R Li, S Chen, S Morgan, SeungJae Lee, Sung Hee Han, Sunghoon Park, Sunshin Kim, TK Lau, Y Wang, Y Wang, Y Yuan, YJ Jeon, YM Lo, YM Lo   +48 more
core   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Non-invasive prenatal testing in mitigating concerns from invasive prenatal diagnostic testing: retrospective assessment of utility in an academic healthcare system in the US

BMJ Open, 2022
Objective Non-invasive prenatal testing (NIPT) is a front-line screening for fatal chromosomal aneuploidy. In pregnant women with a risk of having fetal congenital disorders, NIPT is anticipated to reduce the needs of invasive prenatal diagnostic test ...
Kibum Kim, Linda Kaitlyn Craft
doaj   +1 more source