Results 41 to 50 of about 122,053 (216)

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

open access: yesAdvanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai   +18 more
wiley   +1 more source

An Acute Respiratory Distress Syndrome Patient Successfully Treated with Noninvasive Mechanical Ventilation

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2015
Since still controversial and not often applied, we would like to share our acute respiratory distress syndrome (ARDS) patient successfully treated with noninvasive mechanical ventilation. A 26 year-old male patient with the diagnosis of Burkitt lymphoma
Yusuf Savran   +3 more
doaj   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

open access: yesAdvanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury   +18 more
wiley   +1 more source

AEROSOL THERAPY DURING NON-INVASIVE VENTILATION

open access: yesВестник анестезиологии и реаниматологии, 2018
Nowadays, the effectiveness of inhalation drug therapy during non-invasive ventilation (NIV) has been proved. The delivery of aerosol drugs during non-invasive ventilation depends on numerous factors, such as the choice of inhalation equipment and a mask,
S. N. Аvdeev
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Adaptive non‐invasive ventilation treatment for sleep apnea

open access: yesHealthcare Technology Letters
The purpose of this study was to investigate the effectiveness of two non‐invasive mechanical ventilation (NIV) modalities to treat sleep apnea: (1) Average Volume Assured Pressure Support (AVAPS) NIV, and (2) Pressure Support (PS) NIV with Continuously ...
Fleur T. Tehrani, James H. Roum
doaj   +1 more source

Construction of OSCE evaluation index system for nurses' clinical ability of non⁃invasive positive pressure ventilation

open access: yesHuli yanjiu, 2023
ObjectiveTo construct a scientific,standardized and feasible OSCE evaluation index system for nurses,clinical ability of non-invasive positive pressure ventilation.MethodsBased on literature analysis,OSCE evaluation index system nurses,clinical ability ...
YANG Wenfen, CAI Zhimin, WU Zhengchao
doaj  

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

Cost-Minimization Analysis of Non-Invasive and Invasive Mechanical Ventilation for De Novo Acute Hypoxemic Respiratory Failure in an Eastern European Setting

open access: yesActa Medica Bulgarica, 2019
Introduction: In the light of constant pressure for minimizing healthcare costs we made a cost-minimization analysis comparing invasive mechanical ventilation (IMV) and non-invasive ventilation (NIV) as treatment for hypoxemic acute respiratory failure ...
Ilieva V.   +4 more
doaj   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

open access: yesAdvanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao   +9 more
wiley   +1 more source

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