Results 61 to 70 of about 118 (118)

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai   +4 more
wiley   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

open access: yesExploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang   +4 more
wiley   +1 more source

Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells

open access: yesExploration, EarlyView.
Hypoxia and acidic microenvironments are characteristic features of solid tumors, driving tumor growth, drug resistance, and metastasis. To address these issues, we combined hyperbaric oxygen therapy with rational designed hydroxyethyl starch‐doxorubicin‐copper nanoparticles to modulate the acidic microenvironment of tumors while enhancing the efficacy
Qingyuan Deng   +9 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

Postoperative Management Following Endoscopic Skull Base Reconstruction: A Multidisciplinary Cross‐Sectional Survey

open access: yesHead &Neck, EarlyView.
ABSTRACT Background There is limited consensus on management protocols and practice patterns following endoscopic skull base surgery (ESBS). Methods An online‐based survey focusing on ESBS practice patterns was anonymously distributed to the American Rhinologic Society, North American Skull Base Society, and American Head and Neck Society Skull Base ...
Khodayar Goshtasbi   +15 more
wiley   +1 more source

The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population‐based cohort study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard   +8 more
wiley   +1 more source

Postoperative pain after MiniLap percutaneous versus standard laparoscopic salpingo‐oophorectomy: A propensity‐matched study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The aim of this study was to compare postoperative outcomes in patients undergoing standard laparoscopic salpingo‐oophorectomy versus those using the MiniLap percutaneous surgical system, aiming to demonstrate the non‐inferiority of this ultra‐minimally invasive surgical technique compared to the current gold standard.
Stefano Restaino   +17 more
wiley   +1 more source

Is amnioinfusion for intrapartum variable decelerations effective? Evaluation of the total deceleration area: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Data regarding the efficiency of amnioinfusion in the presence of recurrent variable decelerations (VD) are limited. Total deceleration area (TDA) has been shown to be a useful indicator of both intrapartum fetal acid–base status and neonatal morbidity.
Gal Cohen   +6 more
wiley   +1 more source

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation

open access: yesiMeta, EarlyView.
Multi‐omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)‐derived butyric acid (BA) as a key metabolite in the restoration of valve function in calcific aortic valve disease (CAVD). The therapeutic efficacy of BA in attenuating CAVD progression was confirmed in vitro, ex vivo, and in
Chunli Wang   +18 more
wiley   +1 more source

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

open access: yesJournal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab   +4 more
wiley   +1 more source

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