Results 141 to 150 of about 2,265,753 (326)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Complete heart block in a young adult with non-isolated congenitally corrected transposition of the great arteries: Case report. [PDF]

Ann Med Surg (Lond), 2022
Faraj R, Bachar A, Sidaty O, Bouamoud A, Fassi Fehri Z, Chrifi FZ, Chikhi F, Fellat I, Amri R, Cherti M.   +9 more
europepmc   +1 more source

A Non-Cooperative Game Approach on Isolated Water-Energy Micro-Grids

, 2023
Manuel Fernando Párraga Meneses, José Vuelvas, Arturo Fajardo, Leonardo Rodríguez-Urrego   +3 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Stability and reliability analysis of a non‐isolated high gain DC‐DC converter

IET Power Electronics
This paper investigates the stability and reliability analysis of a non‐isolated high‐gain DC‐DC converter. The proposed DC‐DC converter produces a high gain output voltage with a lower duty ratio and reduced voltage stress on the semiconductor switch. A
Ramachandran Rajesh, Natarajan Prabaharan   +1 more
doaj   +1 more source

Toxic activity against alveolar macrophages of products ofPseudomonas aeruginosaisolated from respiratory and non-respiratory sites [PDF]

, 1976
Ammar H. Al‐Dujaili
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Non-Isolated Fourth-Order Boost DC-DC Converter for Power Management in Low Voltage Low Power DC Grids: Design and Interaction Analysis [PDF]

, 2020
Ashima Kulshreshtha, Anmol Ratna Saxena, Mummadi Veerachary   +2 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Association between Experience of Pet Ownership and Psychological Health among Socially Isolated and Non-Isolated Older Adults. [PDF]

Animals (Basel), 2021
Ikeuchi T, Taniguchi Y, Abe T, Seino S, Shimada C, Kitamura A, Shinkai S.   +6 more
europepmc   +1 more source