Results 161 to 170 of about 13,157,069 (258)
Categorical absorption of a non-isolated singularity
Journal of Noncommutative GeometryWe study an example of a projective threefold with a non-isolated singularity and its derived category. The singular locus can be locally described as a line of surface nodes compounded with a threefold node at the origin. We construct a semiorthogonal decomposition where one component absorbs the singularity in the sense of Kuznetsov–Shinder, and the ...
openaire +2 more sources
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
‘Unbalanced’ anaesthesia and a non‐isolated forearm technique? [PDF]
Anaesthesia, 2013 openaire +2 more sources
Dorsal transscaphoid perilunate dislocation through an isolated scaphoid non-union.
, 1995 An unusual case of a traumatic dorsal transscaphoid perilunate dislocation occurring through an isolated scaphoid non-union is presented.
Baddeley, S, Lam, P
core
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Non-Isolated Resolving Number of Graph with Pendant Edges
, 2019 Journal of Interconnection Networks, Vol. 19, No. 2 (2019) 1950003We consider V; E are respectively vertex and edge sets of a simple, nontrivial and connected graph G. For an ordered set W = fw g of vertices and a vertex v 2 G, the ordered r(vjW) = (d(
Alfarisi, Ridho +3 more
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source