Results 141 to 150 of about 13,157,069 (258)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Non-isolated hypersurface singularities

open access: yes, 1988
Contains fulltext : mmubn000001_06855317x.pdf (Publisher’s version ) (Open Access)
openaire   +1 more source

Review on non-isolated DC-DC converters and their control techniques for renewable energy applications

open access: yes, 2021
Review on non-isolated DC-DC converters and their control techniques for renewable energy ...
F Mumtaz (13435473)   +5 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

PERSISTENT LEFT SUPERIOR VENA CAVA: PERINATAL OUTCOMES, CARDIAC AND GENETIC PROFILES OF ISOLATED AND NON-ISOLATED CASES

open access: yes
Introduction: Persistent left superior vena cava (PLSVC), the most common thoracic venous anomaly, frequently coexists with congenital defects, highlighting its clinical significance.
Huseyin Ekici   +4 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Non-Isolated Resolving Number of Graphs with Homogeneous Pendant Edges

open access: yes, 2018
AIP Conf. Proc. 2014, 020012-1–020012-5; https://doi.org/10.1063/1.5054416A set is called a resolving set of if every vertices of have diff erent r epr esentation.
Alfarisi, Ridho   +4 more
core  

Isolated Non-chylous Pleural Effusion in Two Neonates

open access: yes, 2018
Isolated pleural effusion, so called primary pleural effusion denotes a pleural effusion without documented etiology such as a cardiac, inflammatory, iatrogenic problem or fetal hydrops.
서정수, 황지영, 유정현
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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