Results 221 to 230 of about 2,228,362 (259)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Categorical absorption of a non-isolated singularity

Comment: 31 pages, 2 ...
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Molecular Tracing and Comparative Genomics Analysis of <i>Yersinia pestis</i> Strains Isolated from Wild Rodents in Yunnan Province in 2022. [PDF]

Pathogens
Yang R, Yang F, Dong S, Peng H, Shi L, Wang P.   +5 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Bridging the gap: a review of the factors contributing to differences in vaccination coverage among rural and urban adults. [PDF]

Vaccine
Granade C, Lindley M, Nelson J, Asif A, Zajac J, Reed X.   +5 more
europepmc   +1 more source

Uptake mechanisms and functions of isolated mitochondria in mesenchymal stromal cells. [PDF]

Sci Rep
Kanai M, Goto M, Itakura S, Nishikawa M, Kusamori K.   +4 more
europepmc   +1 more source

Cognitive and neuropsychomotor development in craniosynostosis: an evaluation of the most affected functions. [PDF]

Childs Nerv Syst
Ferreira JL, Gualberto IJN, Da Costa Ribas M, Brandão MM, Tonello C.   +4 more
europepmc   +1 more source