Results 101 to 110 of about 13,385,977 (297)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Research of Isolated Three-Level AC-AC Converter

, 2011
To be used for voltage regulator, An AC-AC direct converter with small bulk has been researched. The paper has proposed an isolated Cuk Three-Level AC-AC Converter.
Lei Li, Ling Zhu
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Non-isolated sextuple output hybrid triad converter configurations for high step-up renewable energy applications

, 2017
This article presents a new non-isolated DC-DC sextuple output hybrid triad converter configurations for high step-up renewable energy applications. Total 8 (eight) converters configurations are obtained by combining SEPIC/SI-SEPIC, Cuk/SI-Cuk, and Boost/
Bhaskar, Mahajan Sagar, Pecht, Michael, Michael Pecht, Dhond, Pranav, Sanjeevikumar, Padmanaban, Mahajan Sagar Bhaskar, Pranav Dhond, Padmanaban Sanjeevikumar, Blaabjerg, Frede; id_orcid, Frede Blaabjerg   +9 more
core   +1 more source

An Isolated Inherently Voltage- and Power- Balanced Bipolar DC Architecture for EV Multi-Outlet Fast-Charging Stations

IEEE Open Journal of Power Electronics
Multi-outlet fast charging stations (MO-FCS) for electric vehicles (EVs) typically employ a front-end AC-DC converter followed by individual unipolar isolated and non-isolated DC-DC converter stages for each outlet, increasing system complexity and also ...
Saghir Amin, Muhammad Awais, Joao L. Afonso, Nuno Costa, Frede Blaabjerg, Vitor Monteiro   +5 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Conversor CC-CC buck+boost multinível bidirecional [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Elétrica, Florianópolis, 2013Este trabalho apresenta uma nova topologia de conversor cc-cc Buck+Boost bidirecional multinível ...
Costa, Levy Ferreira
core  

Boost Multi-port Converter with Simultaneous Isolated DC, Non-isolated DC and AC Outputs

, 2018
In modern residential applications, the dc based power systems are being increasingly implemented for smart and green energy efficient operation. The power requirement for these residential applications can be fulfilled by small localized generation (i.e.
Bhimasingu, Ravikumar, Pinjala Mohana Kishore, Ravikumar Bhimasingu, Pinjala, Mohana Kishore   +3 more
core   +1 more source

DesignandSimulation of High-Efficiency High Gain non Isolated Interleaved DC-DC Converter with Reduced Voltage Stress on the Devices

, 2020
In this paper, a non-isolated two interleaved modified step up KY Converter is analyzed and designed, whose efficiency,the voltage conversion ratio is high.
M.S.Aspalli, Azra Fatima
core   +1 more source