Results 111 to 120 of about 13,385,977 (297)

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Analysis of Non-Isolated Multi-Port Single Ended Primary Inductor Converter for Standalone Applications

, 2018
A non-isolated Multiport Single Ended Primary Inductor Converter (SEPIC) for coordinating photovoltaic sources is developed in this paper. The proposed multiport converter topologies comprise a Single Input Multi yield (SIMO) and Multi Input Multi Output
T. Venkatesan, C. Anuradha, N. Chellammal, C. Sakthivel   +3 more
core   +1 more source

Steady State Analysis of Non-Isolated Single-Input Multi-Output SEPIC Converter for Stand-alone Applications [PDF]

, 2018
This paper proposes a non-isolated three port SEPIC converter for stand-alone photovoltaic applications. The proposed topology uses the Single Input Multi Output (SIMO) structure.
Chellammal, N., Ilambirai, R. C., Anuradha, C., Vijayalakshmi, S., S. Vijayalakshmi, C. Anuradha, N. Chellammal, R. C. Ilambirai   +7 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Novel Non-Isolated Quad-Switched Inductor Double-Switch Converter for DC Microgrid Application

, 2020
In DC microgrid, the combination of energy source, especially renewable with the unit for storage and utility load rely heavily upon the electronics power converters.
Leonowicz, Zbigniew, Mitolo, Massimo, P. Sanjeevikumar, Bhaskar, Mahajan Sagar, Nikita Gupta, Almakhles, Dhafer, Dhafer Almakhles, Subramaniam, Umashankar, Umashankar Subramaniam, Gupta, Nikita, Mahajan Sagar Bhaskar, Massimo Mitolo, Sanjeevikumar, P., Zbigniew Leonowicz   +13 more
core   +1 more source

A Novel High Voltage Gain and Low Voltage Stress DC-DC Boost Converter for Photovoltaic Applications

Majlesi Journal of Electrical Engineering
Photovoltaic (PV) panels are rely on environmental condition such as irradiation or temperature so, they are required to an interface boost converter. Non-isolated DC-DC boost converters have lower volume, lower costs and lower power dissipation compare ...
Mehdi Tabasi, Alireza Bakhshinejad
doaj  

Non-Isolated Zeta PWM DC-DC Power Converter Analysis for CCM Including Parasitics

IEEE Access
This paper presents a theoretical circuit analysis for the non-isolated PWM DC-DC Zeta converter, operated at CCM (Continuous Conduction Mode) in steady-state conditions.
Marian K. Kazimierczuk, Fabio Corti, Gabriele Maria Lozito, Alberto Reatti   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source