Results 81 to 90 of about 3,704 (266)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Performance Analysis of Zeta Converter in Electric Vehicle Applications

ITEGAM-JETIA
The main component of the controller in electric vehicle (EV) is motor,DC-DC converter and charging port.The research analysed the lithium-Ion battery with isolated converter like H bridge and non-isolated type Zeta converters are compared distance ...
V. Nandagopal, Pujari Harish Kumar, N Chinna Alluraiah, K. Harinath Reddy   +3 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

A Non-Isolated Quadratic DC-DC Converter Improved by Voltage-Lift Technique Suitable for High-Voltage Applications

IEEE Access
Non-isolated DC-DC converters are better than isolated converters from aspects such as their lower mass, volume, and cost and higher efficiency and power density. This study proposes a non-isolated high-step-up DC-DC converter.
Hossein Gholizadeh, Mohammadfazel Dehghan, Reza Sharifi Shahrivar, Mohammad Hamed Samimi, Mona Ghassemi   +4 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Time‐optimal finite control set model predictive control of non‐isolated DC–DC converters

IET Electric Power Applications
The authors propose a time‐optimal finite control‐set model predictive control (FCS‐MPC) formulation, generalised to the three most common non‐isolated DC–DC converters (buck, boost, buck–boost) tracking a constant switching frequency.
Thibaut Harzig, Brandon Grainger
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Performance of bidirectional ON-Board Charger in Electric Vehicle: A review

e-Prime: Advances in Electrical Engineering, Electronics and Energy
As per present technological advancement increment of electric vehicles (EVs) in public and private transportation is inevitable. Also, most of the EVs carry batteries as energy transaction/storage units. Generally, it can be observed that, mostly in the
Rajesh Sethuraman, Mageshvaran Rudhramoorthy   +1 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source