Results 61 to 70 of about 3,704 (266)

A Modified Non-Isolated Buck Converter Using Zsource Topology

2026 IEEE 2nd International Conference on Quantum Photonics, Artificial Intelligence & Networking (QPAIN)
The Z-Source Buck topology is used in this study to investigate the methods used to configure a DC-DC converter. In the modern power industry, efficient energy conversion is critical due to the challenges of ineffective power transformation. Compared to conventional Z-Source and Buck converters, the proposed design achieves higher efficiency and output
Al Hossain, Md. Abdullah, Alvy, Md. Asif Imties, Manzurul, Md. Hasan, Mofazzal, Md. Hossain   +3 more
openaire   +2 more sources

Bidirectional DC-DC Converter Topologies for Hybrid Energy Storage Systems in Electric Vehicles: A Comprehensive Review

Energies
Electric Vehicles (EV) significantly contribute to reducing carbon emissions and promoting sustainable transportation. Among EV technologies, hybrid energy storage systems (HESS), which combine fuel cells, power batteries, and supercapacitors, have been ...
Yan Tong, Issam Salhi, Qin Wang, Gang Lu, Shengyu Wu   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Multi-Port Non-Isolated DC-DC Converters and Their Control Techniques for the Applications of Renewable Energy

IEEE Access
In recent times, the increasing demand for energy consumption on a global scale and the prevalent use of power electronics DC-DC converters in various applications, such as hybrid energy systems, hybrid vehicles, aerospace, satellites, and portable ...
R. Aravind, Bharatiraja Chokkalingam, Rajesh Verma, Sakthivel Aruchamy, Lucian Mihet-Popa   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Overview of Bidirectional DC DC Converter for Energy Storage System in Renewable Energy Power Generation

Protek: Jurnal Ilmiah Teknik Elektro
The integration of renewable energy sources (RES), such as wind and solar energy, has become increasingly growth in power generation systems. However, the intermittent and variable nature of these sources poses challenges, especially in maintaining the ...
Tyas Kartika Sari, Dianing Novita Nurmala Putri, Chairul Gagarin Irianto, Maulasukma Widjaja   +3 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source