A Child with Both Langerhans and Non‐Langerhans Cell Histiocytosis
Pediatric Dermatology, 2002Abstract: The histiocytic syndromes consist of a group of disorders that share in common the proliferation of cells of the monocytic/macrophage lineage. It has been conventional to divide the histiocytoses into two separate groups: Langerhans cell histiocytosis (LCH) and non‐LCH.
Ayelet, Shani-Adir +3 more
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Progressive Histiocytosis: Description of a Case of Slow-Course Non-Langerhans Cell Histiocytosis
Dermatology, 2002We describe the case of a 37-year-old male patient who in 1992 started developing a skin eruption characterized by dark red to red-yellow papulonodular lesions that showed no tendency to spontaneous resolution. Visceral organs were not involved and the lipid pattern was basically normal.
R. Caputo +4 more
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Progressive nodular histiocytosis – rare variant of cutaneous non‐Langerhans cell histiocytosis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2006SummaryProgressive nodular histiocytosis is an extremely rare skin disease is clinically characterized by the coincidence of two distinct lesions, namely, superficial xanthomatous papules up to 5 mm and deep nodules and tumors 1–3 cm. Histologically the nodules represent spindle cell xanthogranulomas.
Matthias, Lüftl +3 more
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Endolymphatic Non-Langerhans Cell Histiocytosis of the Larynx
Journal of Pediatric Hematology/Oncology, 2010We report on an uncommon laryngeal non-Langerhans cell histiocytosis. An 11-year-old boy presented with a 6 months history of progressive breath inhibition. Magnetic resonance imaging showed diffuse laryngeal and local lymph node swelling. Histology first resembled sarcoidosis, however, corticosteroids were ineffective.
Carl Friedrich, Classen +4 more
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Primary cerebral non-Langerhans cell histiocytosis: MRI and differential diagnosis
Neuroradiology, 2002We report a young woman with primary cerebral non-Langerhans cell histiocytosis of the juvenile xanthogranuloma family. The clinical course was complicated by extensive infiltration of cranial nerves and meninges and epi- and intramedullary spinal dissemination.
U, Ernemann +5 more
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Intracranial non-Langerhans cell histiocytosis presenting as an isolated intraparenchymal lesion
Pediatric Radiology, 2010Non-Langerhans cell histiocytosis in the absence of cutaneous or other organ involvement is very rare. A Caucasian boy age 3 years 11 months presented with episodes of recurrent right-side seizures over 2 weeks. Brain CT and MR imaging showed a single enhancing left frontal lobe lesion.
Smitha, Rajaram +4 more
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Fibroblastic rheumatism: fibromatosis rather than non‐Langerhans cell histiocytosis
Journal of Cutaneous Pathology, 2010Background: Fibroblastic rheumatism is a unique fibro‐proliferative disease affecting the skin and joints. It is characterized by distinctive clinical and histological features related to benign spindle‐shaped cells proliferation. Pediatric reports are scarce in the literature.
Nicolas, Kluger +4 more
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Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis. Although Langerin protein expression in Langerhans cell histiocytosis has been previously documented, the specificity
Sean K, Lau +2 more
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Suprasellar non-Langerhans cell histiocytosis (Erdheim–Chester disease)—a case report
Clinical Imaging, 2013Erdheim-Chester disease (ECD) is an uncommon non-Langerhans cell histiocytosis that affects multiple body systems and can present clinically in a myriad of ways. An adult onset is most common with bony involvement and constitutional symptoms. We report the case of a 52-year-old female presenting with diabetes insipidus and a suprasellar mass on imaging,
Manas, Sharma +3 more
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A unique non-Langerhans cell histiocytosis with some features of generalized eruptive histiocytoma
Journal of the American Academy of Dermatology, 1994A symmetric eruption of hundreds of coalescent small red macules and a few slightly elevated papules sparing the flexures was observed in a 73-year-old man. Light microscopic examination showed loose aggregates of small and large histiocytic cells. Electron microscopy showed an absence of Langerhans cell granules and lipid droplets.
S, Goerdt +5 more
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