Results 51 to 60 of about 9,762 (221)

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

open access: yesInternational Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang   +5 more
wiley   +1 more source

Histiocytosis: a review focusing on neuroimaging findings

open access: yesArquivos de Neuro-Psiquiatria, 2014
Objective: Histiocytosis is a systemic disease that usually affects the central nervous system. The aim of this study is to discuss the neuroimaging characteristics of Langerhans cell histiocytosis (LCH), the most common of these diseases; and the non ...
Larissa Barcessat Gabbay   +4 more
doaj   +1 more source

Unravelling a hidden case of Erdheim-Chester disease in persistent pericardial effusion

open access: yesRomanian Journal of Cardiology
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell, non-familial multisystemic histiocytosis, with widespread manifestations and of highly variable severity.
Alexandru Trenchea   +6 more
doaj   +1 more source

Solving a Mystery . . . 8 Years Later

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2018
Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis with multisystem involvement and insidious symptoms. In this article, we describe an interesting case of Erdheim-Chester disease that was eventually diagnosed 8 years after symptoms ...
Hayan Jouni MD   +2 more
doaj   +1 more source

Multicentric reticulohistiocytosis: a case report

open access: yesBMC Research Notes, 2018
Background Multicentric reticulohistiocytosis is a rare form of non-langerhans cell histiocytosis presenting with skin changes and erosive arthritis. Infiltration of histiocytes and multinucleated giant cells are typical histological findings and confirm
Azadèh Farokhi   +3 more
doaj   +1 more source

Eosinophilic Granuloma: A Rare and Often Benign Condition Presenting as a Lump on the Head, which was Easily Treated

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2021
Eosinophilic granuloma is a localized, non-invasive form of Langerhans cell histiocytosis. It usually develops in the long bones and is more frequent in children under the age of 10 years. It is very rare in adults.
Tatiana Pires   +5 more
doaj   +1 more source

A rare case of solitary brain Langerhans cell histiocytosis with intratumoral hemorrhage in a patient affected by Turner syndrome [PDF]

open access: yes, 2016
Langerhans cell histiocytosis (LCH) is a rare disease involving clonal proliferation of cells with characteristics similar to bone marrow-derived Langerhans cells. The case of a young woman, affected by Turner syndrome and a solitary intraparenchymal LCH
Alafaci, C.   +5 more
core   +2 more sources

Hidden Insights: Comprehensive Radiological Analysis of Four Skeletal Populations From 13th–19th Century Southern Finland Reveals Neoplastic and Other Lesions Invisible on Bone Surfaces

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study aims to identify lesions confined to the internal structures of bones. A radiographic analysis was performed on 219 archaeological, historical period skeletons from southern Finland. Although the study examines nearly all preserved skeletal elements using plain radiographs, it does not incorporate computed tomography.
Kati Salo   +2 more
wiley   +1 more source

Multisystem Langerhans' cell histiocytosis (Hand-Schüller-Christian disease) in an adult: a case report and review of the literature [PDF]

open access: yes, 2018
Langerhans' cell histiocytosis (LCH) is a rare and enigmatic clonal disorder that affects mainly children. It is characterized by single or multiple granulomatous mass lesions composed of cells with the Langerhans' cell phenotype.
Jaques, B.   +3 more
core  

Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]

open access: yes, 2019
Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta   +8 more
core   +1 more source

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