High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues. [PDF]
International audienceBACKGROUND: Langerhans cell (LC) sarcoma (LCS) is a high-grade neoplasm with overtly malignant cytologic features and an LC phenotype.
A Kanik+38 more
core +4 more sources
Indeterminate cell histocytosis with naïve cells
Histiocytoses are a heterogeneous group of disorders characterized by proliferation and accumulation of cells of mononuclearmacrophage system and dendritic cells.
Sheren F Younes+3 more
doaj +1 more source
Langerhans cells : sensing the environment in health and disease [PDF]
In the last few decades, our understanding of Langerhans cells (LCs) has drastically changed based on novel findings regarding the developmental origin and biological functions of these epidermis-specific resident immune cells.
Deckers, Julie+2 more
core +2 more sources
Erdheim-Chester disease detected with 99MTC MDP bone SPECT/CT
Erdheim-Chester disease (ECD) is a rare non-Langerhans’ cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom.
G Ceulemans+8 more
doaj +1 more source
Localized Langerhans cell histiocytosis masquerading as Brodie s abscess in a 2-year-old child: a case report [PDF]
Langerhans cell histiocytosis (LCH), formerly known as histiocytosis X, refers to a spectrum of diseases characterized by idiopathic proliferation of histiocytes that produce either focal (localized LCH) or systemic manifestations (Hand–Schüller ...
Chang, Wei-Fang+4 more
core +1 more source
Multiple adult xanthogranuloma: case report of successful treatment with CO2 Laser [PDF]
Multiple adult xanthogranuloma is a rare and late variant of Juvenile xanthogranuloma, a non-Langerhans cell histiocytosis. It usually corresponds to a single lesion in adults, and the manifestation of multiples lesions is uncommon.
Alessandra Jaccottet Piriz+2 more
doaj +1 more source
An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey+3 more
core
Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples [PDF]
This review article deals with the analysis and the detection of the morphological features associated with somatic mutations, mostly BRAF(V600E) mutation, on both cytological and histological samples of carcinomas.
Abildgaard+112 more
core +1 more source
What's New? Investigating the spectrum of (likely) pathogenic germline variants (LP/PVs) in hereditary breast and ovarian cancer (HBOC) genes in pediatric malignancies by unselected genotyping identified 44% (12/27) of clinically unsuspected cases. Burden testing demonstrated considerable associations between monoallelic LP/PVs in five HBOC genes and ...
Katharina Daugs+11 more
wiley +1 more source
Juvenile xanthogranuloma of the cerebellopontine angle: A case report and review of the literature
Juvenile xanthogranuloma (JXG) is a non-Langerhans cell histiocytosis, most often presenting with skin lesions of the head, neck, and upper trunk. Intracranial presentations have been previously described, however, due to its rarity, treatment algorithms
Sarah M. Tittman+6 more
doaj +1 more source