Results 121 to 130 of about 6,291,274 (347)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Virtual Full Scale Static Test of a Civil Tilt Rotor Composite Wing in Non-Linear Regime

open access: yesAerospace
This study addresses the crucial role of post-buckling behavior analysis in the structural design of composite aeronautical structures. Traditional engineering practices tend to result in oversized composite components, increasing structural weight. EASA
Antonio Chiariello   +6 more
doaj   +1 more source

A statistical analysis of some non-linear optical effects [PDF]

open access: yes
Statistical analysis of some nonlinear optical effects including scattering light from rotating glass and second harmonic light generated by pseudo-thermal ...
Clark, W.   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

FATIGUE PERFORMANCE ANALYSIS OF CASTING CRANES CONSIDERING NON⁃LINEAR CUMULATIVE DAMAGE

open access: yesJixie qiangdu
Aiming at the fatigue problem of casting cranes in service process,considering the actual service load spectrum,the fatigue performance of casting cranes was analyzed based on the non⁃linear cumulative damage principle.Firstly,the stress time history of ...
YAN MengYu, WEI GuoQian, DUAN RuoChen
doaj  

Sustainable Structural System Selection Using Hybrid Fuzzy Multi-Criteria Decision Model Based on Seismic Performance

open access: yesBuildings
In the rapidly evolving field of sustainable construction, this study aims to address the critical need for advancement in the building industry, focusing on vital indicators like energy efficiency and cost-effectiveness, as well as improving occupant ...
Mohsen Lotfi   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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