Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Effects of non-linear stiffness on performance of an energy harvesting device
Vibration-based energy harvesting devices have received much attention over the past few years due to the need to power wireless devices in remote or hostile environments.
Ramlan, Roszaidi
core +1 more source
Diagnosis of attention deficit hyperactivity disorder using non-linear analysis of the EEG signal. [PDF]
Boroujeni YK, Rastegari AA, Khodadadi H.
europepmc +1 more source
Cross-temporal universality of non-linear dependencies in Asian stock markets [PDF]
This study utilizes the Hinich portmanteau bicorrelation test in conjunction with the windowed testing procedure to examine the cross-temporal universality of non-linear dependencies in the returns series for Asian stock market indices.
Melvin J. Hinich, Kian-Ping Lim
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Phase space methods for non-linear analysis of pedalling forces in cycling. [PDF]
Kunert A +4 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Relationship between short-term exposure to ambient sulfur dioxide and length of hospital stay after surgery for osteoporotic fractures: a distributed lag non-linear analysis. [PDF]
Liu YX +11 more
europepmc +1 more source
Health Impacts of Exposure to Gaseous Pollutants and Particulate Matter in Beijing-A Non-Linear Analysis Based on the New Evidence. [PDF]
Cheng Y, Ermolieva T, Cao GY, Zheng X.
europepmc +1 more source

