Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Advanced lung cancer inflammation index as a diagnostic indicator of bone turnover in osteoporotic fracture patients: a non-linear analysis. [PDF]
Wang J +5 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Detection of exercising ectopic atrial and ventricular beats using non-linear analysis of clinically normal racehorse electrocardiograms at rest or low-intensity exercise. [PDF]
Alexeenko V +8 more
europepmc +1 more source
A Co-Rotational Based Anisotropic Elasto-Plastic Model for Geometrically Non-Linear Analysis of Fibre Reinforced Polymer Composites: Formulation and Finite Element Implementation. [PDF]
Dean A, Safdar N, Rolfes R.
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A simplified homogeneous approach for non-linear analysis of masonry infill panels under in-plane loads. [PDF]
Fang Z, Wang R, Wu P, Sun H, Moradi MJ.
europepmc +1 more source
Non-linear Analysis of Scalp EEG by Using Bispectra: The Effect of the Reference Choice. [PDF]
Chella F +4 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The association between diurnal temperature range and childhood hand, foot, and mouth disease: a distributed lag non-linear analysis. [PDF]
Yin F +6 more
europepmc +1 more source

