Results 141 to 150 of about 6,291,274 (347)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Economic Optimization of Bike-Sharing Systems via Nonlinear Threshold Effects: An Interpretable Machine Learning Approach in Xi’an, China

ISPRS International Journal of Geo-Information
As bike-sharing systems become increasingly integral to sustainable urban mobility, understanding their economic viability requires moving beyond conventional linear models to capture complex operational dynamics.
Haolong Yang, Chen Feng, Chao Gao
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Seizure Onset Zone Lateralization Using a Non-linear Analysis of Micro vs. Macro Electroencephalographic Recordings During Seizure-Free Stages of the Sleep-Wake Cycle From Epilepsy Patients. [PDF]

Front Neurol, 2020
Martínez CGB, Niediek J, Mormann F, Andrzejak RG.   +3 more
europepmc   +1 more source

TERMINATION ANALYSIS OF SAFETY VERIFICATION FOR NON-LINEAR ROBUST HYBRID SYSTEMS

, 2011
Zhikun She
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Which Measures and Parameters of Heart Rate Variability Analysis may be Useful for Early Detection and Predicting Prognosis of Sepsis? A Systematic Review

Türk Yoğun Bakim Derneği Dergisi
Sepsis causes a series of pathological changes, such as cardiovascular, respiratory, and thermoregulation. These changes alter heart rate variability (HRV).
Hasan Kazdağlı, Hasan Fehmi Özel
doaj   +1 more source

Non-Linear Analysis of Void Slab by the Low Tensiotn Constitutive Model

, 2001
Hidenori Yoshida, Tomomasa TAKESHITA, Koji Sakai, Takahiro MORINISHI, Mohamed Boulfiza   +4 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Fully discrete convergence analysis of non-linear hyperbolic equations based on finite element analysis [PDF]

, 2019
Qingli Zhang
openalex   +1 more source