Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Advanced lung cancer inflammation index as a diagnostic indicator of bone turnover in osteoporotic fracture patients: a non-linear analysis. [PDF]
Front Endocrinol (Lausanne)Wang J +5 more
europepmc +1 more source
Non-linear Analysis of Scalp EEG by Using Bispectra: The Effect of the Reference Choice. [PDF]
Front Neurosci, 2017 Chella F +4 more
europepmc +1 more source
Non-linear analysis methods applied to observational and simulated climatic time series
, 2014 Carmen Herrero +1 more
openalex +2 more sources
Correlation between different methods of linear and non-linear analysis in the evaluation of cardiac autonomic modulation in healthy men and women with different levels of cardiorespiratory fitness [PDF]
, 2023 Ana Bárbara Rodrigues Amaral
openalex
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The association between diurnal temperature range and childhood hand, foot, and mouth disease: a distributed lag non-linear analysis. [PDF]
Epidemiol Infect, 2017 Yin F +6 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Hemispheric asymmetry non-linear analysis of EEG during emotional responses from idiopathic Parkinson's disease patients. [PDF]
Cogn Neurodyn, 2016 Yuvaraj R, Murugappan M.
europepmc +1 more source