Non-linear association between metabolic score for insulin resistance and diabetes mellitus in normal-weight middle-aged and older Chinese adults: a multicenter retrospective cohort study. [PDF]
Cai H, Cai Z, Cai Q.
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Non-linear association of the alanine aminotransferase to high-density lipoprotein cholesterol ratio with non-alcoholic fatty liver disease: a secondary analysis of a Chinese cohort. [PDF]
Lin X, Peng Y, Huang J, Huang Z.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Dyslipidemia and aging: the non-linear association between atherogenic index of plasma (AIP) and aging acceleration. [PDF]
Yang Q, Zhu X, Zhang L, Luo F.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Non-linear association between life's essential 8 score and depression in middle-aged and older adults with chronic obstructive pulmonary disease. [PDF]
Shi Y +5 more
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Non-linear association between AKI alert detection rate by physicians and medical costs. [PDF]
Ai HB +7 more
europepmc +1 more source

