Results 91 to 100 of about 192,638 (268)

Fpga Implementations Of Sorters For Non-Linear Filters

open access: yes, 2004
Publication in the conference proceedings of EUSIPCO, Viena, Austria ...
Boaz Hirschl, Leonid P. Yaroslavsky
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Closed-form Filtering for Non-linear Systems

open access: yesCoRR
38 ...
Cantelobre, Théophile   +3 more
openaire   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Amplitude Suppression of Nongaussian Sea Clutter in a Coherent Bandpass Path of the Receiver

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2016
The method of non-linear amplitude suppression of radar clutter from a sea surface in the coherent band path of the receiver is considered. The model of the most adequate nongaussian radar clutter from the rough sea surface which envelope is based on K ...
E. A. Milashchenko, A. A. Yazovsky
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Amplitude suppression of nongaussian sea clutter in a noncoherent bandpass path of the receiver

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2016
The method of non-linear amplitude suppression of radar clutter from a sea surface in a noncoherent band path of the receiver is considered. The model of the most adequate nongaussian a radar clutter from the rough sea surface which envelope is based on ...
E. A. Milashchenko, A. A. Yazovsky
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Fingerprint frequency normalisation and enhancement using two‐dimensional short‐time Fourier transform analysis

open access: yesIET Computer Vision, 2016
A fingerprint image with non‐uniform ridge frequencies can be considered as a two‐dimensional dynamic signal. A non‐uniform stress on the sensing area applied during fingerprint acquisition may result in a non‐linear distortion that disturbs the local ...
Mubeen Ghafoor   +2 more
doaj   +1 more source

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