Results 61 to 70 of about 70,789 (216)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On the Holographic Spectral Effects of Time-Interval Subdivisions
Quantum ReportsDrawing on formal parallels between scalar diffraction theory and quantum mechanics, it is demonstrated that quantum wavefunction propagation requires a holographic model of time.
Sky Nelson-Isaacs
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Journal of World-Systems Research, 2022 This article is a follow-up to a previous essay that mapped the dynamics of the modern world-system theory into what was called a Global Power-Field (GPF) during the colonial era phase of planetary history.
Omer Awass
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Anomalous universal conductance as a hallmark of non-locality in a Majorana-hosted superconducting island. [PDF]
Nat Commun, 2022 Hao Y, Zhang G, Liu D, Liu DE.
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
On Ontological Alternatives to Bohmian Mechanics
Entropy, 2018 The article describes an interpretation of the mathematical formalism of standard quantum mechanics in terms of relations. In particular, the wave function ψ(x) is interpreted as a complex-valued relation between an entity (often called &ldquo ...
Thomas Filk
doaj +1 more source
The Potential of a Thick Present through Undefined Causality and Non-Locality. [PDF]
Entropy (Basel), 2022 Capurso A.
europepmc +1 more source