Results 141 to 150 of about 21,008 (258)

Placebo in Paediatric Clinical Trials: Systematic Literature Review and Framework‐Based Synthesis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Introduction Placebo‐controlled trials can provide strong evidence on safety and efficacy, but their ethical acceptability in paediatric research is contested because children have limited decisional capacity and placebo use may entail withholding effective therapy.
Georgia Parry, Artur Abelian, Chloe C. E. Williams, Lydia E. Roberts, Megan Athersmith, Louise Oni   +5 more
wiley   +1 more source

Ethical principles in health care research [PDF]

, 2013
Chapter topics • The history of the evolving recognition of the need to regulate research involving human subjects • Consideration of some key ethical principles relevant to the research process • Applying ethical understanding in the practice ...
Scott, Anne
core  

Resisting Psychopathologies of Dominance and Authoritarianism: From Trumpian Dystopia to Better Tomorrows

Journal of Psychiatric and Mental Health Nursing, EarlyView.
ABSTRACT Background The world and mental health nursing face several crises that, in different ways, reflect problems of dominance. Global politics are afflicted with a growth of support for right‐wing ideologies associated with domineering authoritarian leaders.
Michael Haslam, Mick McKeown
wiley   +1 more source

Do deepfakes, digital replicas and human digital twins justify personality rights?

The Journal of World Intellectual Property, EarlyView.
Abstract Unauthorised deepfakes are deeply problematic, from the spreading of misinformation to non‐consensual pornographic content. This paper asks whether deepfakes, digital replicas and human digital twins justify personality rights. To address this question, it examines the harms that deepfakes can cause through disinformation, demeaning content ...
Hayleigh Bosher
wiley   +1 more source

Construction and validation of a questionnaire for the analysis of bioethical conceptions [PDF]

, 2012
In this paper we describe the stages of a quantitative questionnaire development that allows the investigation of conceptions about bioethical values inherent to the scientific activity. This questionnaire was statistically and semantically validated and
Araújo, Elaine Sandra Nicolini Nabuco de, Caldeira, Ana Maria de Andrade, Silva, Paloma R.   +2 more
core  

Becoming Dostoevsky (how Rowan Williams opens up Bakhtin)

Modern Theology, EarlyView.
Abstract With the end of Communism in Russia, non‐materialist contexts were enthusiastically restored to Mikhail Bakhtin's globally famous ideas of carnival, dialogism, and polyphony. This essay surveys Rowan Williams's 2008 study Dostoevsky: Language, Faith + Fiction as a major contribution to this effort, concentrating on those general philosophical ...
Caryl Emerson
wiley   +1 more source

Ethics of overtreatment and undertreatment in older adults with cancer

BMC Medical Ethics
Background Over-/undertreatment are pervasive in older adults with cancer, and challenges arise in applying the principles of bioethics: beneficence, nonmaleficence, justice, and patient autonomy.
Clark DuMontier, William Dale, Anna C. Revette, Jane Roberts, Ameya Sanyal, Neha Perumal, Eric C. Blackstone, Hajime Uno, Mary I. Whitehead, Lewis Mustian, Tammy T. Hshieh, Jane A. Driver, Gregory A. Abel   +12 more
doaj   +1 more source

Radical dystopia: The comic modernism of George Orwell's Nineteen Eighty‐Four

Orbis Litterarum, EarlyView.
Abstract The present essay turns the received view of George Orwell's Nineteen Eighty‐Four on its head, arguing that Orwell's dystopian classic mobilizes the modernist techniques of T. S. Eliot's The Waste Land to lampoon the ideological fatalism of Eliot and other cultural conservatives.
Magnus Ullén
wiley   +1 more source

The struggle over caesarean section on maternal request: an ethical principles approach to Swedish media portrayal

Reproductive Health
Background Caesarean section on maternal request (CSMR) is a complex ethical issue. Sweden is an intriguing case for studying CSMR due to its restrictive policy that curtail women autonomous choice regarding the mode of birth, despite overall policy ...
Mio Fredriksson, Magdalena Mattebo
doaj   +1 more source

Middlebrow Aesthetics: An Explanation and Defense

Pacific Philosophical Quarterly, EarlyView.
ABSTRACT We offer a philosophical account of the middlebrow as a theoretical category to do explanatory and critical work in aesthetics. On our account, the middlebrow ought to be understood as aspirational popular art. That is, it is art which aspires both to be popular (in a distinctive sense), and at the same time to be something more than popular ...
Aaron Meskin, Jonathan M. Weinberg
wiley   +1 more source