Results 231 to 240 of about 223,220 (289)

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern, Cassie Turner, Rishendran Naidoo, David Godbolt, Amy Ives, Kirsten Popplewell, Zarnie Lwin, Sally Pearson, Kimberley Nelson, Jason Madore, William C Dougall, Brett G. M. Hughes   +11 more
wiley   +1 more source

Global, regional, and national trends in the burden of melanoma and non-melanoma skin cancer: insights from the global burden of disease study 1990-2021. [PDF]

Sci Rep
Zhou L, Zhong Y, Han L, Xie Y, Wan M.
europepmc   +1 more source

Rates of Self‐Reported Skin Cancer in Current and Retired Elite Australian Cricketers

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background Skin cancer rates are high in Australians, outdoor workers and physically active people. Australia is currently preparing a roadmap to better assess high risk groups for consideration of more targeted skin screening. Methods The membership of the Australian Cricketers Association (ACA), both current and retired cricketers, was ...
John W. Orchard, Georgia Redmayne, Brad Stenner, Alex J. Chamberlain, Andrew Ming, Philippa Inge, Leona Yip   +6 more
wiley   +1 more source

Gene-Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy. [PDF]

Cells
Jasmine F, Almazan A, Khamkevych Y, Argos M, Shahriar M, Islam T, Shea CR, Ahsan H, Kibriya MG.   +8 more
europepmc   +1 more source

Vulval Lichen Sclerosus Associated With Immune Checkpoint Inhibitor Therapy: A Case Series of 11 Patients

Australasian Journal of Dermatology, EarlyView.
ABSTRACT There have only been a limited number of case reports that have described vulval lichen sclerosus in patients receiving immune checkpoint inhibitor (ICI) therapy. We describe 11 cases of vulval lichen sclerosus in patients with melanoma treated with ICIs, and in nine of these cases, the lichen sclerosus symptoms began after ICI commencement ...
Sophie Walter, Francesca Watts, Raquel Ruiz Araujo, Thevaki Wain, Amanda Glanz, Diona Damian, Matteo S. Carlino, Alexander M. Menzies, Georgina V. Long, Linda K. Martin   +9 more
wiley   +1 more source

Unraveling the landscape of non-melanoma skin cancer through single-cell RNA sequencing technology. [PDF]

Front Oncol
Yan G, Wang X, Zhang G.
europepmc   +1 more source

Mapping the Current Demand and Supply of Dermatologists and General Practitioners Managing Skin Cancer in Queensland, Australia

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives The rising incidence of skin cancer places a significant burden on Australia's health workforce. To support workforce planning, we estimated the supply of dermatologists and general practitioners (GP) working in skin cancer medicine, service demand and need across Queensland in 2023.
Daniel Lindsay, Shaun Stangl, Kiana Ronagh, Jessica Cameron, Richard Johns, Jim Muir, Louisa G. Collins   +6 more
wiley   +1 more source

Margins in head and neck non-melanoma skin cancer surgery: clinical/pathological criteria and their impact on oncological outcomes and therapeutic choices. A systematic review. [PDF]

Acta Otorhinolaryngol Ital
Bussu F, Daloiso A, Pagliuca G, Settimi S, Scanu A, Margani V, Mele DA, Di Stefano V, Bonomo M, Cazzador D, Parrilla C, Rizzo D, Zanoletti E, Nicolai P, Gallo A, Galli J.   +15 more
europepmc   +1 more source

Occupational Sun Exposure and Melanoma Development: A Review of the Evidence

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Cutaneous melanomas arise through a number of causal pathways, all of which involve exposure to sunshine or artificial ultraviolet (UV) radiation to some extent. Their initiation also depends on host factors that determine susceptibility to melanoma, and whether the UV exposure is intermittent or chronic.
David C. Whiteman, Gabrielle J. Williams, John F. Thompson   +2 more
wiley   +1 more source

Erythema nodosum, malignant melanoma and non-melanoma skin cancer in relation to inflammatory bowel disease: a Mendelian randomization study. [PDF]

Sci Rep
Zhao Y, Shao Y, Zhou J, Pei J, Chong J, Lu C, Chen Y.   +6 more
europepmc   +1 more source