Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus
Meiosis is a key cellular process of sexual reproduction that includes pairing of homologous sequences. In many species however, meiosis can also involve the segregation of supernumerary chromosomes, which can lack a homolog.
Michael Habig+2 more
doaj +1 more source
A Least Squares Regression Model to Detect Quantitative Trait Loci with Polar Overdominance in a Cross of Outbred Breeds: Simulation [PDF]
A least squares regression interval mapping model was derived to detect quantitative trait loci (QTL) with a unique mode of genomic imprinting, polar overdominance (POD), under a breed cross design model in outbred mammals. Tests to differentiate POD QTL
Jong-Joo Kim, Jack C. M. Dekkers
doaj +1 more source
Mendelian Inheritance Pattern and High Mutation Rates of Microsatellite Alleles in the Diatom Pseudo-nitzchia multistriata [PDF]
The diatom Pseudo-nitzschia multistriata exhibits a diplontic life cycle composed of an extensive phase of vegetative cell division and a brief phase of sexual reproduction.
Amos+50 more
core +1 more source
The next 10 years of behavioural genomic research
Three transformative developments for behavioural genomic research in the next 10 years are described. First, behavioural genomic research will use dimensional measures to reveal the hierarchical genetic architecture of psychopathology. A second direction for behavioural genomic research will be to investigate causa models of GE interplay.
Robert Plomin
wiley +1 more source
Episodic neurologic disorders: syndromes, genes, and mechanisms. [PDF]
Many neurologic diseases cause discrete episodic impairment in contrast with progressive deterioration. The symptoms of these episodic disorders exhibit striking variety.
Fu, Ying-Hui+2 more
core +2 more sources
Mendelian and non-Mendelian inheritance of newly-arisen chromosome rearrangements [PDF]
Seven centric shifts and three reciprocal interchanges, all newly-arisen in natural populations, have been tested for their inheritance in the dioecious flowering plant Rumex acetosa. In backcrosses between the heterozygote and standard plants transmissions ranged from 0.36 to 0.85 per gamete for the novel chromosome.
A S Wilby, J S Parker
openaire +3 more sources
Interaction of Prions Causes Heritable Traits in Saccharomyces cerevisiae. [PDF]
The concept of "protein-based inheritance" defines prions as epigenetic determinants that cause several heritable traits in eukaryotic microorganisms, such as Saccharomyces cerevisiae and Podospora anserina.
Anton A Nizhnikov+6 more
doaj +1 more source
Perspectives on the Genomics of HSP Beyond Mendelian Inheritance
Hereditary Spastic Paraplegia is an extraordinarily heterogeneous disease caused by over 50 Mendelian genes. Recent applications of next-generation sequencing, large scale data analysis, and data sharing/matchmaking, have discovered a quickly expanding ...
Dana M. Bis-Brewer+3 more
doaj +1 more source
Heterogeneous earning responses to inheritance: new event-study evidence from Norway [PDF]
It has long been assumed that inheritances, particularly large ones, have a negative effect on the labor supply of inheritors. Using Norwegian registry data, I examine the inheritance-induced decline in inheritors' wages and occupational income. In contrast to prior research, my estimates allow the dynamic effect of inheritances on labor supply to vary
arxiv
Nuclear mutations affecting mitochondrial structure and function in Chlamydomonas [PDF]
Wild type cells of the green alga Chlamydomonas reinhardtii can grow in the in the dark by taking up and respiring exogenously supplied acetate. Obligate photoautotrophic (dark dier, dk) mutants of this alga have been selected which grow at near wild ...
Boynton, J. E.+2 more
core +1 more source