Results 121 to 130 of about 109,513 (348)
Inheritance of Properties of Spectra [PDF]
Mathematical Notes, 2010, Vol. 88, No. 6, pp. 100-110, 2009 A mechanism for the inheritance of properties of spectra by differential spectra is developed and applied to prove geometric properties of morphisms of differential algebraic varieties.
arxiv +1 more source
Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype. [PDF]
PLoS Genetics, 2019 Transmission ratio distortion (TRD) by the mouse t-haplotype, a variant region on chromosome 17, is a well-studied model of non-Mendelian inheritance.
Yves Charron +5 more
doaj +1 more source
A comparison of SNPs and microsatellites as linkage mapping markers: lessons from the zebra finch (Taeniopygia guttata) [PDF]
, 2010 Background: Genetic linkage maps are essential tools when searching for quantitative trait loci (QTL). To maximize genome coverage and provide an evenly spaced marker distribution a combination of different types of genetic marker are sometimes used.
Ball, A.D. +5 more
core +3 more sources
Molecular Mechanisms of Non-Mendelian Inheritance in Genetic Diseases
Medical Principles and Practice, 1994 Recently identified molecular mechanisms (mitochondrial DNA mutations, genomic imprinting, uniparental disomy, unstable trinucleotide repeats) responsible for the non-Mendelian patterns of some genetic diseases are reviewed. Among the diseases considered are LHON (Leber’s hereditary optic neuropathy), MERRF (myoclonic epilepsy with ragged-red fibers ...
Sadika A. Al-Awadi +2 more
openaire +2 more sources
Animal Models and Experimental Medicine, EarlyView.In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang +6 more
wiley +1 more source
A heritable switch in carbon source utilization driven by an unusual yeast prion [PDF]
, 2009 Several well-characterized fungal proteins act as prions, proteins capable of multiple conformations, each with different activities, at least one of which is self-propagating.
Brown, Jessica C.S., Lindquist, Susan
core +2 more sources
Molecular Ecology Resources, EarlyView., 2023 Abstract There is growing interest in the role of structural variants (SVs) as drivers of local adaptation and speciation. From a biodiversity genomics perspective, the characterization of genome‐wide SVs provides an exciting opportunity to complement single nucleotide polymorphisms (SNPs). However, little is known about the impacts of SV discovery and
Jana R. Wold +4 more
wiley +1 more source
Hyper-IgE syndrome. Lessons from function and defects of STAT-3 or DOCK-8
Revista Alergia México, 2016 In the classification of primary immunodeficiencies, hyper-IgE syndrome, identified with OMIM code # 147060 in the Online Mendelian Inheritance in Man catalog, belongs to the group of syndromes associated with combined immunodeficiencies.
Julio César Alcántara-Montiel +1 more
doaj +1 more source
Discovering new hub genes of dilated cardiomyopathy
ESC Heart Failure, EarlyView.Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu +9 more
wiley +1 more source
Molecular Ecology Resources, EarlyView., 2023 Abstract Identifying sex‐linked markers in genomic datasets is important because their presence in supposedly neutral autosomal datasets can result in incorrect estimates of genetic diversity, population structure and parentage. However, detecting sex‐linked loci can be challenging, and available scripts neglect some categories of sex‐linked variation.
Diana A. Robledo‐Ruiz +7 more
wiley +1 more source