Results 11 to 20 of about 79,198 (289)

Maternal non-Mendelian inheritance of a reduced lifespan? A hypothesis. [PDF]

J Assist Reprod Genet, 2014
A negative correlation exists between advanced maternal age and reproduction. Current data suggest that this correlation is due to a decline in oocyte quality with respect to female age. Since a new individual is derived from the fusion of a single sperm and egg, we tested whether the quality of this material could influence the long-term physiological
Wilding M, Coppola G, De Icco F, Arenare L, Di Matteo L, Dale B.   +5 more
europepmc   +6 more sources

Colorectal Cancer Risk between Mendelian and Non-Mendelian Inheritance. [PDF]

Clin Colon Rectal Surg, 2023
AbstractHereditary colorectal cancer has been an area of focus for research and public health practitioners due to our ability to quantify risk and then act based on such results by enrolling patients in surveillance programs. The wide access to genetic testing and whole-genome sequencing has resulted in identifying many low/moderate penetrance genes ...
Hibler EA, Szymaniak B, Abbass MA.
europepmc   +5 more sources

Non-Mendelian inheritance during inbreeding of Ca_v3.2 and Ca_v2.3 deficient mice. [PDF]

Sci Rep, 2020
AbstractThe mating of 77 heterozygous pairs (Cav3.2[+|−] x Cav3.2[+|−]) revealed a significant deviation of genotype distribution from Mendelian inheritance in weaned pups. The mating of 14 pairs (Cav3.2[−|−] female x Cav3.2[+|−] male) and 8 pairs (Cav3.2[+|−] female x Cav3.2[−|−] male) confirmed the significant reduction of deficient homozygous Cav3.2[
Alpdogan S, Clemens R, Hescheler J, Neumaier F, Schneider T.   +4 more
europepmc   +5 more sources

Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in the Non-mendelian Inheritance-Mediated Feather Growth Rate in Chicken. [PDF]

Biochem Genet
Qiu M, Zhang Z, Zhu S, Liu S, Peng H, Xiong X, Chen J, Hu C, Yang L, Song X, Xia B, Yu C, Yang C.   +12 more
europepmc   +3 more sources

RNAi epimutations conferring antifungal drug resistance are inheritable [PDF]

Nature Communications
Epimutations modify gene expression and lead to phenotypic variation while the encoding DNA sequence remains unchanged. Epimutations mediated by RNA interference (RNAi) and/or chromatin modifications can confer antifungal drug resistance and may impact ...
Carlos Pérez-Arques, María Isabel Navarro-Mendoza, Ziyan Xu, Grit Walther, Joseph Heitman   +4 more
doaj   +2 more sources

Non-Mendelian inheritance: Genomic Imprinting

, 2023
Genomic imprinting is a form of non-Mendelian inheritance. It refers to a parental-specific difference in the behaviour of homologous chromosomes or loci. Genes are expressed from two alleles; one maternal and one paternal. But in minor cases, genomic imprinting causes the differential expression of a gene according to its maternal or paternal origin ...
Ayşen Tezel, Meltem Arıkan, Zeynep Yüce   +2 more
openalex   +3 more sources

Clarifying Mendelian vs non-Mendelian inheritance. [PDF]

Genetics
Abstract Gregor Mendel developed the principles of segregation and independent assortment in the mid-1800s based on his detailed analysis of several traits in pea plants. Those principles, now called Mendel's laws, in fact, explain the behavior of genes and alleles during meiosis and are now understood to underlie “Mendelian inheritance”
Strome S, Bhalla N, Kamakaka R, Sharma U, Sullivan W.   +4 more
europepmc   +5 more sources

Epistatic Control of Non-Mendelian Inheritance in Mouse Interspecific Crosses [PDF]

Genetics, 1996
Abstract Strong deviation of allele frequencies from Mendelian inheritance favoring Mus spretus-derived alleles has been described previously for X-linked loci in four mouse interspecific crosses. We reanalyzed data for three of these crosses focusing on the location of the gene(s) controlling deviation on the X chromosome and the ...
Xavier Montagutelli, Rowena Turner, Joseph H. Nadeau   +2 more
openalex   +3 more sources

Mendelian and non-Mendelian inheritance of newly-arisen chromosome rearrangements [PDF]

Heredity, 1988
Seven centric shifts and three reciprocal interchanges, all newly-arisen in natural populations, have been tested for their inheritance in the dioecious flowering plant Rumex acetosa. In backcrosses between the heterozygote and standard plants transmissions ranged from 0.36 to 0.85 per gamete for the novel chromosome.
A S Wilby, Joe Parker
openalex   +3 more sources

Non-mendelian Inheritance in Mammals Is Highly Constrained [PDF]

Cell, 2018
In this issue, Kazachenka, Bertozzi, and colleagues identify elements in the mouse genome with epigenetic variability between littermates, a phenomenon linked to transmission of phenotypes over generations. This addresses two questions that remained unanswered despite intense speculation: how prevalent are these alleles, and what is their effect ...
Luke Isbel, Dirk Schübeler
openalex   +3 more sources