Results 191 to 200 of about 79,198 (289)

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake, Melissa P. Swan, Kari J. Ekenstedt   +2 more
wiley   +1 more source

Faculty Opinions recommendation of Assessing non-Mendelian inheritance in inherited axonopathies.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2021
openaire   +2 more sources

Integrative machine learning approach for identifying genes associated with quantitative traits: A soybean (Glycine max) yield case study

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract To improve the identification of minor‐effect molecular markers and genes associated with quantitative traits, addressing inefficiencies in traditional molecular marker mining and the limited impact of these markers in practical breeding, we analyzed over 15,000 soybean (Glycine max) genotypes across nine maturity groups using an AI‐driven ...
Wei Zhou, Haoyong Ouyang, Zhengxiao Yan, Jiayi Song, Yichan Li, Zhou Tang, Chang Zhao   +6 more
wiley   +1 more source

Decision letter for "Can non‐Mendelian inheritance of extrachromosomal circular DNA‐mediated EPSPS gene amplification provide an opportunity to reverse resistance to glyphosate?"

, 2020

openalex   +1 more source

Clinically Irrelevant Terminal 16q21 Deletion Detected by NIPT Is Attributable to Inherited Fragility at FRA16B

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 348-352, February 2026.
ABSTRACT Genome‐wide non‐invasive prenatal testing (NIPT) is a powerful tool for prenatal detection of the common aneuploidies causing Down‐, Edwards‐, and Patau syndrome. Its genome‐wide reach also enables the detection of unbalanced structural chromosomal abnormalities.
Servi J. C. Stevens, Wanwisa van Dijk, Nicole Y. Souren, Merryn V. E. Macville, Guillaume van de Zande, Brigitte H. W. Faas, Bart de Koning, Arthur van den Wijngaard, Sonja de Munnik, Masoud Zamani Esteki   +9 more
wiley   +1 more source

CRISPR‐Cas9‐Generated TXNDC15 c.560delA Homozygous Mouse Model Exhibits Meckel–Gruber Syndrome Phenotype

genesis, Volume 64, Issue 1, February 2026.
ABSTRACT To determine whether TXNDC15 variation causes Meckel–Gruber syndrome (MKS), we assessed the pathogenicity of the frameshift variant c.560delA. A CRISPR–Cas9 generated mouse model carrying the equivalent Txndc15 c.512delA mutation was analyzed at embryonic day 15.5.
Yang Liu, Hui Wang, Liyuan Chen, Xiaoxia Wu, Zhiyong Xu, Qingfa Huang, Hu Zhang, Xiushu Cao, Xinyuan Liang, Xingjian Zhong, Caiqun Luo   +10 more
wiley   +1 more source

Evaluation of Transgenerational Gene Editing Efficiency and Inheritance of Edits Using a Split Cas9/gRNA Crossing System in Zea mays

Plant Biotechnology Journal, EarlyView.
Christian Damian Lorenzo, Lennert Impens, Matilde Sanches, Wout Vandeputte, Pieter Wytynck, Stijn Aesaert, Griet Coussens, Dirk Inzé, Hilde Nelissen, Laurens Pauwels   +9 more
wiley   +1 more source

The parabss1 Drosophila melanogaster as Model for Chronic Nociception: Insights Into Cannabidiol Analgesic Effects

European Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Chronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies have identified voltage‐gated sodium (Nav) channels, particularly gain‐of‐function mutations such as L858F and R1150W in human NaV1.7, as involved in the development of chronic pain. Methods A chronic pain model was
Serena Mares Malta, Lucas Ian Veloso Correia, Alexandre Souza Marquez, Lucas Matos Martins Bernardes, John George Howland, Ana Paula Mendes‐Silva, Foued Salmen Espíndola, Carlos Ueira‐Vieira   +7 more
wiley   +1 more source

Identifying Causal Genotype–Phenotype Relationships for Population‐Sampled Parent–Child Trios

Genetic Epidemiology, Volume 50, Issue 1, February 2026.
ABSTRACT The process by which genes are transmitted from parent to child provides a source of randomization preceding all other factors that may causally influence any particular child phenotype. Because of this, it is natural to consider genetic transmission as a source of experimental randomization.
Yushi Tang, Irineo Cabreros, John D. Storey   +2 more
wiley   +1 more source

Analysis of family history data for evidence of non-Mendelian inheritance resulting from vertical transmission. [PDF]

, 1977
Paul Fine
openalex   +1 more source