Hybrid dysgenesis: from darkness into light:a commentary on 'Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility' by William R.Engels [PDF]
, 2007 DAVID J. FINNEGAN +3 more
core +1 more source
A Similarity Matrix for Preserving Haplotype Diversity Amongst Parents in Genomic Selection
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT In genomic selection, balancing genetic gain with the preservation of genetic diversity is a critical challenge, requiring innovative approaches to parent selection. Traditional methods risk losing valuable genetic diversity by not fully accounting for the complex patterns of haplotype distribution.
Abdulraheem A. Musa, Norbert Reinsch
wiley +1 more source
Pathogenic variants prevalence patients with diabetic kidney disease in Japan: A descriptive study
Journal of Diabetes Investigation, EarlyView.Previous studies have identified pathogenic variants in 22% of Caucasian patients with diabetic kidney disease (DKD); however, this proportion may vary depending on ethnicity and updates to the database. Whole‐genome sequencing of 79 patients with DKD in Japan revealed that 34.1% had kidney‐related heterozygous pathogenic variants, and 12.7% had ...
Toyohiro Hashiba +5 more
wiley +1 more source
Sodium-Glucose Transporter 2: Untangling the Mingled Yarn of Genetic and Pharmacologic Inhibition. [PDF]
Kidney360Gulati A.
europepmc +1 more source
Genome-wide association studies, Polygenic Risk Scores and Mendelian randomisation: an overview of common genetic epidemiology methods for ophthalmic clinicians. [PDF]
Br J OphthalmolLee SS +3 more
europepmc +1 more source
Epileptic spasms and RNA analysis in a new case of Kabuki syndrome type 2
Epilepsia, EarlyView.
Flavia Privitera +3 more
wiley +1 more source
A Principled Framework for Mendelian Randomization in Oral Health Research
Journal of Periodontal Research, EarlyView.This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir +5 more
wiley +1 more source
Genetically Transitional Disease and the Road to Personalized Medicine. [PDF]
Genes (Basel)Yao Q, Gorevic PD, Gibson G.
europepmc +1 more source
Type 2 diabetes as a risk factor for promoting hypertrophic scar formation after wound healing: a two-sample mendelian randomization study. [PDF]
Arch Dermatol ResZheng W +8 more
europepmc +1 more source