Results 31 to 40 of about 79,198 (289)
Epigenetic regulation by heritable RNA. [PDF]
PLoS Genetics, 2014 Genomic concepts are based on the assumption that phenotypes arise from the expression of genetic variants. However, the presence of non-Mendelian inheritance patterns provides a direct challenge to this view and suggests an important role for ...
Reinhard Liebers +2 more
doaj +1 more source
Induced mutations for studying Mendelian inheritance
Journal für Kulturpflanzen, 2022 All genetic variation results from mutations. Orders of magnitude can increase mutation rates by applying irradiation or chemical treatment. Genome editing offers new perspectives for mutation induction because mutation sites can be precisely targeted ...
Christian Jung
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B chromosome and its non-Mendelian inheritance in Atractylodes lancea. [PDF]
PLoS OneSupernumerary B chromosomes contribute to intraspecific karyotypic variation. B chromosomes have been detected in more than 2000 organisms; they possess unique and diverse features, including non-Mendelian inheritance. Here, we report one or more B chromosomes in the gynodioecious plant Atractylodes lancea. Among 54 A.
Hara K +7 more
europepmc +3 more sources
Evidence for Non‐Mendelian Inheritance in Spastic Paraplegia 7 [PDF]
Movement Disorders, 2020 Abstract Background Although the typical inheritance of spastic paraplegia 7 is recessive, several reports have suggested that SPG7 variants may also cause autosomal dominant hereditary spastic paraplegia (HSP).
Mehrdad A. Estiar +19 more
openaire +2 more sources
Genetic and Epigenetic Inheritance at Telomeres
Epigenomes, 2022 Transgenerational inheritance can occur at telomeres in distinct contexts. Deficiency for telomerase or telomere-binding proteins in germ cells can result in shortened or lengthened chromosome termini that are transmitted to progeny.
Evan H. Lister-Shimauchi +3 more
doaj +1 more source
Bezmiâlem Science, 2020 Mutations in genes encoding the formation of ion channels may cause epileptic syndromes. These epileptic syndromes are generally divided into generalized and partial epilepsies.
Halil Aziz VELİOĞLU +1 more
doaj +1 more source
Environmental Factors Can Influence Mitochondrial Inheritance in the Saccharomyces Yeast Hybrids. [PDF]
PLoS ONE, 2017 Mitochondria play a critical role in the generation of metabolic energy and are crucial for eukaryotic cell survival and proliferation. In most sexual eukaryotes, mitochondrial DNA (mtDNA) is inherited from only one parent in non-Mendelian inheritance in
Yu-Yi Hsu, Jui-Yu Chou
doaj +1 more source
An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors [PDF]
, 2015 Background: Identification of one or several disease causing variant(s) from the large collection of variants present in an individual is often achieved by the sequential use of heuristic filters.
Bosmans, Tim +8 more
core +5 more sources
Genetics of Childhood Epilepsy
Pediatric Neurology Briefs, 2000 Genetic epilepsies are classified according to the mechanism of inheritance in three major groups: 1) Mendelian idiopathic epilepsies; 2) Non-Mendelian or “complex” epilepsies; and 3) Chromosomal disorders.
J Gordon Millichap
doaj +1 more source
Ferroportin-related haemochromatosis associated with novel Y64H mutation of the SCL40A1 gene [PDF]
, 2014 In this paper we described the first Polish patient with ferroportin disease. Hereditary haemochromatosis (HH) is a condition associated with universal iron overload, and it is divided into four types, according to the Online Mendelian Inheritance in Man
Caleffi, Angela +3 more
core +1 more source