Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease. [PDF]
, 2019 The MHC region is highly associated with autoimmune and infectious diseases. Here we conduct an in-depth interrogation of associations between genetic variation, gene expression and disease.
Aguiar +76 more
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Interaction of Prions Causes Heritable Traits in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2016 The concept of "protein-based inheritance" defines prions as epigenetic determinants that cause several heritable traits in eukaryotic microorganisms, such as Saccharomyces cerevisiae and Podospora anserina.
Anton A Nizhnikov +6 more
doaj +1 more source
Genome-wide search for strabismus susceptibility loci. [PDF]
, 2003 The purpose of this study was to search for chromosomal susceptibility loci for comitant strabismus. Genomic DNA was isolated from 10mL blood taken from each member of 30 nuclear families in which 2 or more siblings are affected by either esotropia or ...
Fujiwara, Hirotake +6 more
core +1 more source
Future trends in Animal Breeding due to new genetic tecnologies
, 2011 The Darwin theory of evolution by natural selection is based on three principles: (a) variation; (b) inheritance; and (c) natural selection. Here, I take these principles as an excuse to review some topics related to the future research prospects in ...
Toro Ibañez, Miguel Angel
core +1 more source
A heritable switch in carbon source utilization driven by an unusual yeast prion [PDF]
, 2009 Several well-characterized fungal proteins act as prions, proteins capable of multiple conformations, each with different activities, at least one of which is self-propagating.
Brown, Jessica C.S., Lindquist, Susan
core +2 more sources
Perspectives on the Genomics of HSP Beyond Mendelian Inheritance
Frontiers in Neurology, 2018 Hereditary Spastic Paraplegia is an extraordinarily heterogeneous disease caused by over 50 Mendelian genes. Recent applications of next-generation sequencing, large scale data analysis, and data sharing/matchmaking, have discovered a quickly expanding ...
Dana M. Bis-Brewer +3 more
doaj +1 more source
Mendelian Inheritance Pattern and High Mutation Rates of Microsatellite Alleles in the Diatom Pseudo-nitzchia multistriata [PDF]
, 2012 The diatom Pseudo-nitzschia multistriata exhibits a diplontic life cycle composed of an extensive phase of vegetative cell division and a brief phase of sexual reproduction.
Amos +50 more
core +1 more source
Hyperalphalipoproteinemia and Beyond: The Role of HDL in Cardiovascular Diseases
Life, 2021 Hyperalphalipoproteinemia (HALP) is a lipid disorder characterized by elevated plasma high-density lipoprotein cholesterol (HDL-C) levels above the 90th percentile of the distribution of HDL-C values in the general population.
Antonina Giammanco +7 more
doaj +1 more source
Inheritance of flower colour in Desmodium gangeticum (L.) DC. [PDF]
Electronic Journal of Plant Breeding, 2014 The present experiment was conducted with the aim to study the inheritance pattern of flower colour in Desmodium gangeticum. Populations of two parental lines having two different flower colours, white (DDG 18) and pink (DDG 8) were used for study.
Harshwardhan R. Nandanwar* and P. Manivel
doaj
Frontiers in Genetics, 2011 Epigenetic information can be passed on from one generation to another via DNA methylation, histone modifications and changes in small RNAs, a process called epigenetic memory.
Zoe eMigicovsky, Igor eKovalchuk
doaj +1 more source