Results 91 to 100 of about 40,360 (291)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Analysis of impurity spaces as a percentage volume of non-metallic inclusions

Production Engineering Archives, 2015
The parameters of high-grade steel are influenced by a combination of factors, including chemical composition and production technology. The impurity content is also a key determinant of the quality of high-grade steel. Non-metallic inclusions are one of
Tomasz Lipiński
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effect of Ti and S Content on the Properties and Machinability of Low-Carbon Ferritic–Pearlitic Steel

Metals
This research was focused on the effect of Ti and S content on the formation of non-metallic inclusions and their influence on the mechanical properties and machinability of low-carbon ferritic–pearlitic steels.
Boštjan Arh, Franc Tehovnik, Franci Vode, Bojan Podgornik   +3 more
doaj   +1 more source

Effect of BOF-RH-CC and BOF-LF-CC Process on Cleanness of Cold Heading Steel ML08Al

Teshugang, 2022
The types and quantity density of non-metallic inclusions, and the change of total oxygen in steel ML08Al produced by the two processes BOF-RH-CC and BOF-LF-CC are analyzed.
屠兴圹, 徐建飞, 杨成威, 苏振伟, 黄云飞   +4 more
doaj  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Interaction mechanism of non-metallic particles with crystallization front

Archives of Metallurgy and Materials, 2017
The process of steel solidification in the CCS mould is accompanied by a number of phenomena relating to the formation of non-metallic phase, as well as the mechanism of its interaction with the existing precipitations and the advancing crystallization ...
Żak P. L., Kalisz D., Rączkowski G.
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Microscopic Mechanism of Shear Bands in Amorphous Solids

, 2012
The fundamental instability responsible for the shear localization which results in shear bands in amorphous solids remains unknown despite enormous amount of research, both experimental and theoretical.
Dasgupta, Ratul, Hentschel, H. George E., Procaccia, Itamar   +2 more
core   +1 more source