Results 41 to 50 of about 10,355,181 (279)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Algorithm for quantifying the particle size distribution of non-metallic inclusions formation in steel production [PDF]

open access: yes, 2021
When the quantitative characterization of non-metallic inclusions in steel is done and the effect of limiting factors is assessed, and based on that the possibility of reconstruction of the total content of non-metallic inclusions in steel is estimated ...
Raić, Karlo, Mihailovic, Marija
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The Effect of microstructural heterogeneities on the fatigue behaviour of 22MnB5 sheet steel [PDF]

open access: yes, 2013
This work deals with the effect of heat treatment on the fatigue strength of a rear axial beam and aims to propose a methodology suitable and reliable for fatigue design.
PESSARD, Etienne   +4 more
core  

Effect of ladle-lining materials on inclusion evolution in Al-killed steel during LF refining

open access: yesHigh Temperature Materials and Processes
The effect of lining materials (Al2O3 and Al2O3–MgO·Al2O3) of ladle on evolution of non-metallic inclusions in aluminum-killed (Al-killed) steel during ladle furnace refining without Ca treatment was investigated through industrial experiments.
Gao Fu-bin   +4 more
doaj   +1 more source

Current research and latest developments on refractories used as ladle linings

open access: yes工程科学学报, 2019
Non-metallic inclusions significantly influence the properties of steels. Take heavy rail steel as an example, Al2O3 inclusions can become fatigue source under cyclic stress, resulting in the rupture of the steel.
WANG En-hui, CHEN Jun-hong, HOU Xin-mei
doaj   +1 more source

Effect of non-metallic inclusions on cleavage fracture

open access: yesMaterials Science and Technology, 1986
Abstract The effect of non-metallic inclusions on cleavage in wrought steel has been studied using a resulphurized mild steel. The cleavage fracture stress was measured at –196°C and found to exhibit an orientation dependence which is attributed to the morphology of the inclusions.
T. J. Baker, F. P. L. Kavishe, J. Wilson
openaire   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Factors Analysis of Non-Aqueous Electrolytic Extraction of Ultrafine Non-Metallic Inclusions

open access: yes, 2011
It will be no damage for small non-metallic inclusions by non-aqueous electrolytic technique. However, there are some unsolved problems: the interference of by-product, the corrosion of small inclusions and the low efficiency.
Hui Gai Li   +4 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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