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Revisiting non-obstructive azoospermia: Is there a best way to retrieve testicular sperm? [PDF]

Reprod Med Biol
Microdissection TESE has been considered the “gold standard” for retrieving testicular sperm in cases of non‐obstructive azoospermia (NOA) despite limited scientific support.
Kanto S, Ichioka K, Sato Y, Uchino Y, Tanaka T, Endo M.   +5 more
europepmc   +4 more sources

Health risks associated with infertility and non-obstructive azoospermia. [PDF]

Asian J Androl
Non-obstructive azoospermia is a common condition associated with significant health risks, including increased mortality, cancer, and chronic diseases such as metabolic and cardiovascular disorders.
Huyghe E, Chiu PK.
europepmc   +5 more sources

A comparison of the expression patterns and diagnostic capability of the ncRNAs NEAT1 and miR-34a in non-obstructive azoospermia and severe oligospermia [PDF]

Human Genomics
Infertility is a major global health problem, affecting 8–12% of couples worldwide, with male causes contributing to approximately 50% of cases. Notably, around 15% of infertile men are azoospermic.
Aya Salman, Abdullah F. Radwan, Olfat G. Shaker, Adel A., Ghadir A. Sayed   +4 more
doaj   +3 more sources

Novel mutations of TEX11 are associated with non-obstructive azoospermia [PDF]

Frontiers in Endocrinology, 2023
Non-obstructive azoospermia (NOA) affects 10% of infertile men worldwide, and genetic studies revealed that there are plenty of monogenic mutations that responsible for a part of idiopathic NOA cases.
Jian Song, Yanwei Sha, Xiaojun Liu, Xuhui Zeng, Xiuling Zhao   +4 more
semanticscholar   +5 more sources

Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia [PDF]

Reproductive Biology and Endocrinology, 2022
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han, Lin Hao, Zhenduo Shi, Ying Li, Liang Wang, Zhenbei Li, Qiang Zhang, Fangfang Hu, Yijuan Cao, Kun Pang, Zuobin Zhu   +10 more
doaj   +2 more sources

Secretory azoospermia or non-obstructive azoospermia?

Folia Histochemica et Cytobiologica, 2010
In the non-obstructive azoospermia versus the secretory azoospermia it is first necessary to have a clear assessment and definition and then takes care of the patient before the surgical sampling taking into account the age of the woman and in fine try ...
J M Rigot
doaj   +4 more sources

Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells

Nature Communications, 2020
Non-obstructive azoospermia affects 1% of men. Here, authors perform single-cell transcriptomic analysis of human testicular cells from healthy donors and non-obstructive azoospermia patients and find that inhibition of Wnt signaling promotes the ...
Liangyu Zhao, Chencheng Yao, Chao Yang
exaly   +2 more sources

Insulin-like Peptide-6 Levels in Non-obstructive Azoospermia

Journal of the College of Physicians and Surgeons Pakistan, 2022
To investigate the serum versus insulin-like peptide-6 (INSL-6) levels in men with non-obstructive azoospermia (NOA) and normospermia.Descriptive study.Department of Urology, Balikligol State Hospital and Harran University, Sanliurfa, Turkey, between July and October 2020.The serum and seminal levels of INSL-6 were measured in men with NOA, and ...
Kemal Gümüş, Mehmet Demir, İsmail Dağ   +2 more
openalex   +4 more sources

Global Andrology Forum (GAF) Clinical Guidelines on the Management of Non-obstructive Azoospermia: Bridging the Gap between Controversy and Consensus. [PDF]

World J Mens Health
Purpose Non-obstructive azoospermia (NOA), defined as the absence of sperm in the ejaculate due to testicular failure, is observed in 5% to 15% of infertile men and accounts for two-thirds of azoospermia cases.
Hamoda T, Shah R, Mostafa T, Pinggera GM, Atmoko W, Rambhatla A, Al Hashimi M, Çayan S, Colpi GM, Alipour H, Ko E, Zini A, Dimitriadis F, Rashed A, Park HJ, Saleh R, Toprak T, Ryzhkov A, Kadıoğlu A, Kandil H, Kalkanli A, El-Sakka AI, Calik G, Falcone M, Elbardisi H, Arafa M, Ho CCK, Martinez MP, Binsaleh S, Motawi AT, Gherabi N, Tsujimura A, Taniguchi H, Kosgi R, Calogero AE, Shatylko T, Kim D, Thomas C, Tadros NN, Andreadakis S, Musa MU, Konstantinidis C, Preto M, Le TV, Khalafalla KM, Cannarella R, Bowa K, Balagobi B, Katz DJ, Nguyen Q, Tanwar R, Borges Junior E, Agarwal A.   +52 more
europepmc   +2 more sources

Identification of novel cytoskeleton protein involved in spermatogenic cells and sertoli cells of non-obstructive azoospermia based on microarray and bioinformatics analysis. [PDF]

BMC Med Genomics
During mammalian spermatogenesis, the cytoskeleton system plays a significant role in morphological changes. Male infertility such as non-obstructive azoospermia (NOA) might be explained by studies of the cytoskeletal system during spermatogenesis.
Hashemi Karoii D, Azizi H, Darvari M, Qorbanee A, Hawezy DJ.   +4 more
europepmc   +2 more sources