Results 101 to 110 of about 54,369 (287)

Prevalence of Y chromosome deletions in a Brazilian population of nonobstructive azoospermic and severely oligozoospermic men [PDF]

, 2003
We determined the prevalence of Y chromosome deletions in a population of 60 Brazilian nonobstructive azoospermic and severely oligozoospermic men. PCR-based screening of microdeletions was performed on lymphocyte DNA for the presence of 14 sequence ...
Avellar, Maria Christina Werneck, Cedenho, Agnaldo Pereira, Fraietta, Renato, Porto, Catarina Segreti, Spaine, Deborah Montagnini, Srougi, Miguel, São Pedro, Simone Lima   +6 more
core   +2 more sources

A WHO 2021‐based comprehensive scheme outlining sperm parameters’ associations with IVF outcomes in PGT‐A cycles

Andrology, EarlyView.
Abstract Objective To examine the association between semen parameters, assessed according to World Health Organization (WHO)‐2021 criteria, and paternal body mass index (BMI) and age, with embryological and clinical outcomes in ICSI cycles involving preimplantation genetic testing for aneuploidy (PGT‐A).
Rossella Mazzilli, Danilo Cimadomo, Federica Innocenti, Marilena Taggi, Greta Chiara Cermisoni, Sara Ginesi, Lisa Dovere, Laura Albricci, Maurizio Guido, Maria Rosaria Campitiello, Susanna Ferrero, Antonio Capalbo, Alberto Vaiarelli, Filippo Maria Ubaldi, Alberto Ferlin, Laura Rienzi, Gianluca Gennarelli   +16 more
wiley   +1 more source

Distribution and number of Cajal-like cells in testis tissue with azoospermia

Kaohsiung Journal of Medical Sciences, 2017
We investigated the number and distribution of Cajal-like cells in patients with azoospermia. A total of 99 patients with non-obstructive azoospermia were divided into subgroups [19 patientsin hypospermatogenesis group (S1), 40 patients in maturation ...
Eray Hasirci, Tahsin Turunc, Nebil Bal, Mehmet Resit Goren, Huseyin Celik, Enis Kervancioglu, Ayhan Dirim, Mustafa Agah Tekindal, Hakan Ozkardes   +8 more
doaj   +1 more source

Deletions within the azoospermia factor subregions of the Y chromosome in Hong Kong Chinese men with severe male-factor infertility: controlled clinical study. [PDF]

, 2000
OBJECTIVE: To determine the patterns and the prevalence of microdeletions in the azoospermia factor subregions of the Y chromosome in Hong Kong Chinese men with severe male-factor infertility. DESIGN: Controlled clinical study.
Ho, PC, Lau, EY, Ng, EH, So, WW, Tse, JY, Yeung, WS   +5 more
core  

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse [PDF]

, 2015
Genome‐wide recombination is essential for genome stability, evolution, and speciation. Mouse Tex11, an X‐linked meiosis‐specific gene, promotes meiotic recombination and chromosomal synapsis.
Anderson LK, David C Page, de los Santos T, Fang Yang, Helen Skaletsky, Janet D Marszalek, Laura G Brown, McCarrey JR, N Adrian Leu, P Jeremy Wang, Robert D Oates, Sherman Silber, Steve Rozen   +12 more
core   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. [PDF]

, 2020
Male factor infertility is a problem in today's society but many underlying causes are still unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) knockout mouse line (SCCx43KO) has provided a translational model ...
Behr, Rüdiger, Brehm, Ralph HJ, Distl, Ottmar, Hilbold, Erika, Hoedemaker, Martina, Jung, Klaus, Langeheine, Marion, Metzger, Julia, Rajkovic, Aleksandar, Rode, Kristina, Wilkening, Sandra   +10 more
core   +1 more source

Comprehensive Analysis of the Association Between Human Non-obstructive Azoospermia and Plasticisers via Single-Cell and Traditional RNA Sequencing Methods

Exposure and Health, 2022
A father’s lifetime experience is a major risk factor for a range of diseases in an individual. The influences of exposure can also be transmitted to offspring.
Xu Zhang, Xiaohan Ren, Tongtong Zhang, Xiang Zhou, Xinglin Chen, Hongcheng Lu, Xuan Zhou, Xiaolei Zhang, Shangqian Wang, Chao Qin   +9 more
semanticscholar   +1 more source

Initial motility and vitality predict the semen quality after long‐term cryostorage, even in patients with restricted ejaculate parameters

Andrology, EarlyView.
Abstract Background Cryopreservation of human semen is the cornerstone for preserving male fertility before gonadotoxic therapy or in cases of high variability in semen parameters. This is particular crucial in cases of severe oligoasthenoteratozoospermia (OAT), where diminished sperm counts may compromise planned intracytoplasmic sperm injection (ICSI)
Simone Bier, Daniela Hanke, Michael Zitzmann, Sabine Kliesch, Verena Nordhoff   +4 more
wiley   +1 more source

Impact of age at first visit on glycolipid metabolism, bone metabolism, and fertility potential in patients with Klinefelter syndrome

Andrology, EarlyView.
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli, Andrea Graziani, Noemi Sagone, Andrea Di Nisio, Massimo Iafrate, Fabrizio Dal Moro, Alberto Ferlin, Andrea Garolla   +7 more
wiley   +1 more source