Difficulties in differential diagnosis between obstructive and non-obstructive azoospermia
Introduction. The difference between obstructive and non-obstructive azoospermia (OA and NOA) is important for the choice of treatment tactics and adequate counseling of a married couple.Objective.
S. I. Gamidov +5 more
doaj +1 more source
Background: Intracytoplasmic sperm injection (ICSI) opens the gate for many cases of male factor infertility to be the biological fathers of their sibling since 1992.
Ali A. Abo-Alshaar +2 more
doaj +1 more source
Sperm retrieval techniques in azoospermic patients: PESA, MESA, TESA, TESE and MICROTESE [PDF]
Azoospermia is defined as the absence of mature spermatozoa in semen analysis after centrifugation. The causes of azoospermia may be related to spermatogenesis defects and classified as non-obstructive azoospermia, or to the obstruction of the efferent ...
Marcelo Vieira, Sidney Glina
doaj
Management of the Infertile Male with Azoospermia
Azoospermia means the complete absence of spermatozoa upon examination of the semen. Azoospermia may result from a lack of spermatozoa production in the testicles, or from an inability of produced spermatozoa to reach the emitted semen.
Erdem Akbay, Mesut Tek
doaj +1 more source
Analysis of Y Chromosome Microdeletions and Mutation in Exon7 of the STAG3 Gene in Iranian Infertile Men with Idiopathic Non-Obstructive Azoospermia [PDF]
Background: Azoospermia is defined as the absence of sperm in the semen and is divided in two types; obstructive and non-obstructive azoospermia. Non-obstructive azoospermia include approximately 60% of azoospermia patients.
Sara Pouriamanesh +5 more
doaj
Serum estradiol levels in infertile men with non-obstructive azoospermia
Purpose: To report the different patterns of estradiol levels in infertile men with non-obstructive azoospermia and correlate these levels with their clinical and laboratory findings.
Nader Salama, Saeed Blgozah
doaj +1 more source
Sperm retrieval techniques for assisted reproduction
Different surgical methods such as PESA, MESA, TESA, TESE and micro-TESE have been developed to retrieve spermatozoa from either the epididymis or the testis according to the type of azoospermia, i.e., obstructive or non-obstructive.
Sandro C. Esteves +2 more
doaj +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Correlation of serum FSH and rate of testicular sperm retrieval in non-obstructive azoospermia
Background: Sperm retrieval from men with azoospermia has evolved in recent times, providing patient hope for fulfilling their dream of having their own genetic child through testicular sperm extraction followed by intracytoplasmic sperm injection (TESE ...
Kaberi Banerjee +2 more
doaj +1 more source
Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang +14 more
wiley +1 more source

