Cryopreservation of testicular and epididymal sperm: techniques and clinical outcomes of assisted conception [PDF]
The introduction of the technique of intracytoplasmic sperm injection to achieve fertilization, especially using surgically retrieved testicular or epididymal sperm from men with obstructive or non-obstructive azoospermia, has revolutionized the field of
Bhushan K. Gangrade
doaj +4 more sources
Altered microRNA expression in patients with non-obstructive azoospermia [PDF]
Abstract Background MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are indicated to play essential roles in spermatogenesis. However, little is known about the expression patterns or function of miRNAs in human testes involved in infertility.
Jie Lian+7 more
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Ooplasmic injection of elongating spermatids for the treatment of non- obstructive azoospermia [PDF]
We applied the technique of ooplasmic elongating spermatid injection to the treatment of non-obstructive azoospermia. Mature oocytes were injected with elongating spermatids isolated from testicular biopsy material obtained from 13 non-obstructed azoospermic men.
Nikolaos Sofikitis+13 more
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Microsurgical TESE and the distribution of spermatogenesis in non-obstructive azoospermia [PDF]
We wished to map the distribution of spermatogenesis in different regions of the testis in 58 men with non-obstructive azoospermia, and to develop a rational microsurgical strategy for the testicular sperm extraction (TESE) procedure. One goal was to maximize the chances for retrieving spermatozoa from such men, to minimize tissue loss and pain, and to
Sherman J. Silber
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Non-obstructive azoospermia: current and future perspectives [PDF]
Infertility affects 1 in 6 couples, and male factor infertility has been implicated as a cause in 50% of cases. Azoospermia is defined as the absence of spermatozoa in the ejaculate and is considered the most extreme form of male factor infertility. Historically, these men were considered sterile but, with the advent of testicular sperm extraction and ...
Tharakan, T+3 more
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Synaptic defects at meiosis I and non-obstructive azoospermia [PDF]
Recent advances in immunofluorescence methodology have made it possible to directly monitor protein localization patterns in germ cells undergoing meiosis. We used this technology to examine the early stages of meiosis in testicular material obtained from men presenting for evaluation at infertility clinics.Specifically, we compared meiotic progression,
Daniel Topping+6 more
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Value of ultrasound in the etiological diagnosis of azoospermia [PDF]
Objective: To explore the application value of ultrasound in the etiological diagnosis of azoospermia.Methods: Three hundred and fourteen consecutive cases of azoospermia diagnosed in our hospital from January 1, 2015 to December 31, 2021 were ...
YAO Shifa, CHEN Ping, LI Liang, NIU Jianmei
doaj +1 more source
Varicocele treatment in non-obstructive azoospermia: a systematic review [PDF]
Objective: To review the available literature and identify factors associated with successful outcomes after varicocele repair (VR) in the setting of non-obstructive azoospermia (NOA). Methods: The PubMed and EMBASE databases were searched for relevant articles.
Stephanie Jensen, Edmund Y. Ko
openaire +3 more sources
The gene regulatory role of non-coding RNAs in non-obstructive azoospermia
Non-coding RNAs are classified as small non-coding RNAs, long non-coding RNAs and circular RNAs, which are involved in a variety of biological processes, including cell differentiation, proliferation, apoptosis and pathological conditions of various ...
Guanqing Zhou+15 more
doaj +1 more source
Health risks associated with infertility and non-obstructive azoospermia. [PDF]
Abstract Non-obstructive azoospermia is a common condition associated with significant health risks, including increased mortality, cancer, and chronic diseases such as metabolic and cardiovascular disorders. This review aims to highlight the potential health challenges faced by men with this condition compared to fertile counterparts ...
Huyghe E, Chiu PK.
europepmc +4 more sources