Results 101 to 110 of about 4,733,796 (328)

NON-PARAMETRIC AND SEMI-PARAMETRIC TECHNIQUES FOR MODELING AND SIMULATING CORRELATED, NON-NORMAL PRICE AND YIELD DISTRIBUTIONS: APPLICATIONS TO RISK ANALYSIS IN KANSAS AGRICULTURE [PDF]

Parametric, non-parametric, and semi-parametric approaches are commonly used for modeling correlated distributions. Semi-parametric and non-parametric approaches are used to examine the risk situation for Kansas agriculture.
Featherstone, Allen M., Kastens, Terry L.   +1 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Evaluation of gamma diversity of reef corals (Scleractinia) in the Mexican Pacific Evaluación de la diversidad gama de corales arrecifales (Scleractinia) en el Pacífico de México

Revista Mexicana de Biodiversidad, 2010
In order to assess gamma diversity of hermatypic corals, maximum likelihood methods (Chao, Jacknife) and resampling (bootstrap) were used over a database with 3 423 records of corals from 15 regions of the Mexican Pacific. Analysis were conducted for the
Héctor Reyes-Bonilla, Luis E. Calderón-Aguilera, Gabriela Cruz-Piñón, Ramón Andrés López-Pérez, Pedro Medina-Rosas   +4 more
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A Comparison of Parametric and Non-Parametric Selection Indices for Selecting Corn Hybrids in the Brazilian Cerrado

Agronomy
The selection of superior maize genotypes is complex due to the quantitative and intercorrelated nature of agronomic traits and their strong environmental influence, which limits the efficiency of direct selection and requires multivariate approaches ...
Felipe Zôrzo, Renato Fernando Amabile, Carolaini Campos da Silva, Juaci Vitória Malaquias, João Victor Pinheiro Melo, Arlini Rodrigues Fialho, Bárbara Soares Aires França, Marcelo Fagioli   +7 more
doaj   +1 more source

GDP nowcasting with ragged-edge data: a semi-parametric modeling [PDF]

This paper formalizes the process of forecasting unbalanced monthly datasets in order to obtain robust nowcasts and forecasts of quarterly gross domestic product (GDP) growth rate through a semi-parametric modeling.
Dominique Guegan, Laurent Ferrara, Patrick Rakotomarolahy   +2 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Relative Efficiency of Active Labour Market Policies: Evidence from a Social Experiment and Non-Parametric Methods [PDF]

We re-analyze the effects of a Danish active labour market program social experiment that included a range of sub-treatments, including monitoring, job search assistance and training.
Rosholm, Michael, Svarer, Michael, Vikström, Johan   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Ceiling effects in the Movement Assessment Battery for Children-2 (MABC-2) suggest that non-parametric scoring methods are required

PLoS ONE, 2018
Initially designed to identify children’s movement impairments in clinical settings, the Movement Assessment Battery for Children-2 (MABC-2) is also widely used to evaluate children’s movement in research.
Blandine French, Nicole J. Sycamore, Hannah L. McGlashan, C. Blanchard, N. Holmes   +4 more
semanticscholar   +1 more source