Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Words standarization by non-parametric statistical methods
, 2001 The author has dealt with amalgamation of pattern primitives and its justification in language description, in earlier studies [4] & [5]. Here an attempt is being made to apply distribution free techniques, more commonly known as non-parametric ...
Dhami, H.S.
core
Estimating the resilience of non-stationary systems. [PDF]
Nat CommunSmith T, Morr A, Schötz C, Boers N.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Regional development assessment using parametric and non-parametric ranking methods: A comparative analysis of Slovenia and Croatia [PDF]
In this paper we describe several regional development-assessment methods and subsequently apply them in a comparative development level analysis of the Slovenian and Croatian municipalities.
Jaksa Puljiz +5 more
core
Methods for analyzing recurrent and terminal events considering composite and competing endpoints in clinical trials: a practical overview. [PDF]
BMC Med Res MethodolDuoerkongjiang A +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
A Non-Parametric Microsimulation Approach to Assess Changes in Inequality and Poverty [PDF]
This paper presents a non-parametric microsimulation methodology for assessing the determinants of changes in income inequality and poverty. One great advantage of this method over alternatives is that it is not very demanding in terms of modelling ...
Rob Vos, Marco V. Sánchez
core
Trimester-specific reference interval for glycated hemoglobin in non-diabetic pregnant women: A cross-sectional study. [PDF]
Clinics (Sao Paulo)Takiso K +4 more
europepmc +1 more source